how long did the first 24kg take for people at the low doses
#semaglutide 2025-12-04
Thursday43 messages9 participantstimes are UTC
Highlights from this day
- nausea_window — i stayed on 1.7 for 25 months and never went to 2.4, appetite was already where i needed it 18:08
- nausea_window — lost about 4kg on the low doses before i even got to 1, which surprised me 18:10
- turnaround_tam — STEP is several trials, so saying STEP said x is usually wrong without a number after it, i have it written down somewhere 18:53
- vial_ledger — is the plateau usually appetite coming back or just the scale stopping 19:59
my dose day drifted from friday to sunday, does that reset anything
does the licensed ceiling for weight differ from the diabetes one
vials not pens here
i stayed on 1.7 for 25 months and never went to 2.4, appetite was already where i needed it
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lost about 4kg on the low doses before i even got to 1, which surprised me
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dose day is sunday for me only because thats when i remember, not because sunday matters
anyone compared their 2 vial dosing against the pen increments
my 30 vial in 1ml gives 2.5mg/ml so 1 lands on 20 units, thats why i picked that volume
i held at 12 for 9 months and it was the best decision i made
went too fast once
thats STEP 1
restarted after 8 months off at a low dose and the nausea arrived exactly like the first time
moving my dose day by a day or two never did anything noticeable for me
im 18 months in at 5 and the appetite effect faded, is that a thing
same dose day
i was wrong about the ceiling for a year, i thought 3 existed. it doesnt for the weight indication
STEP is several trials, so saying STEP said x is usually wrong without a number after it, i have it written down somewhere
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if youre comparing brand to compounded, dose accuracy in the vial is the variable, not the molecule
while im here what did SELECT actually measure, i see it quoted for everything
STEP 4 had the withdrawal arm, thats the one people quote when they talk about stopping
steady state takes weeks
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how many weeks before you noticed anything at 1.7
not the same trial
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follow up the trials titrated on a fixed schedule, most people here dont, worth remembering when comparing
licensed ceiling for weight is 2.4 weekly, anything above that is not a licensed dose
is the plateau usually appetite coming back or just the scale stopping
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mine faded too
update on the earlier thing half life is about a week so youre roughly four to five weeks to steady state on any new dose
held there too
the appetite effect faded for me around 25 months and going up fixed it for a while
4 months at 2.4 and the honest summary is diminishing returns after the first half
vial units and pen clicks are different systems, mixing the two is how people end up wrong
follow up held at 1 and lost 19lb over 4 months, slower than the trials and fine by me
seven days ish
is the plateau at 14 weeks normal or am i doing something wrong
[edited]my Janoshik report on the MKM vial came back 99.2 against a certificate saying 97.4
going slow cost me nothing except time and saved me two bad weeks, thats my whole contribution
is 2.4 the top or do people go past it
my plateau was the scale stopping while appetite stayed suppressed, which is a different problem
2.4 is the ceiling
SELECT wasnt weight
Purity check: no report on file for lot C-4402. Nothing logged either way.
went to 2.4 and the extra suppression wasnt worth the GI for me, so i came back down
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