did anyone hold at 0.25 longer than four weeks before going up
#semaglutide 2026-02-06
Friday20 messages5 participantstimes are UTC
Highlights from this day
- factory_direct_fi — FLOW was the kidney outcomes trial and it gets quoted in here for things it didnt measure 14:51
- VialBot — Channel stats, last 30 days: 50 messages from 38 members. 14:52
- nordic_price_nils — STEP is several trials, so saying STEP said x is usually wrong without a number after it, not advice obviously steady state is the bit people skip, judging a new dose… 15:22
- nordic_price_nils — quick one is there a reason to hold at 1.7 rather than going to 2.4 16:45
vial units and pen clicks are different systems, mixing the two is how people end up wrong, ymmv
moving my dose day by a day or two never did anything noticeable for me
changed my mind on the four week rule, i think it depends entirely on how the current dose feels
FLOW was the kidney outcomes trial and it gets quoted in here for things it didnt measure
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Channel stats, last 30 days: 50 messages from 38 members.
give it four weeks
wk 1-4 0.25mg
wk 5-10 0.50mg (held 2 extra weeks)
wk 11-14 1.00mg
wk 15-26 1.70mg (held, long)
wk 27+ 2.40mgmine faded too
im 14 months in at 7.5 and the appetite effect faded, is that a thing
the appetite effect faded for me around 16 months and going up fixed it for a while
seven days ish
whats the actual licensed ceiling, i keep seeing different numbers
i stayed on 1.7 for 24 months and never went to 2.4, appetite was already where i needed it
brand vs compounded, is there a difference people can actually feel
going slow cost me nothing except time and saved me two bad weeks, thats my whole contribution
STEP is several trials, so saying STEP said x is usually wrong without a number after it, not advice obviously
steady state is the bit people skip, judging a new dose after eight days tells you almost nothing
the trials titrated on a fixed schedule, most people here dont, worth remembering when comparing
vials not pens here
compounded and brand felt the same to me at 2, which is one person and nothing more
went 1 to 1.7 too fast and spent two weeks regretting it, dropped back and repeated the step, i could be wrong
how long did the first 37kg take for people at the low doses
quick one is there a reason to hold at 1.7 rather than going to 2.4
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