vialroom

#semaglutide 2026-02-09

Monday16 messages5 participantstimes are UTC
Highlights from this day
  • coelution_cai — dose day is sunday for me only because thats when i remember, not because sunday matters lost about 7kg on the low doses before i even got to 1, which surprised me 11:33
  • coelution_cai — the trials titrated on a fixed schedule, most people here dont, worth remembering when comparing, your mileage will differ 11:38
  • coelution_cai — vial units and pen clicks are different systems, mixing the two is how people end up wrong 11:53
LU

does moving my dose day by two days matter with a seven day half life

CC

while im here lost about 23kg on the low doses before i even got to 1, which surprised me

LU

five week steps worked better for me than four, purely on how the second week felt

PF

give it four weeks

Cited study
Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes (SELECT)
New England Journal of Medicine · 2023
Hard cardiovascular endpoints in people with overweight or obesity and established disease.
CC

dose day is sunday for me only because thats when i remember, not because sunday matters
lost about 7kg on the low doses before i even got to 1, which surprised me

Cited study
Once-Weekly Semaglutide in Adults with Overweight or Obesity and Type 2 Diabetes (STEP 2)
The Lancet · 2021
The type 2 diabetes population, where the weight response is generally smaller.
⚠️1🤝1📈6

update on the earlier thing anyone gone from 15 straight to 1.7 or is that too big a jump

the trials titrated on a fixed schedule, most people here dont, worth remembering when comparing, your mileage will differ

🤝1👀5💀10
KF

did anyone titrate slower than four weeks a step and how did that go

my plateau was the scale stopping while appetite stayed suppressed, which is a different problem