plateaus move
#semaglutide 2026-03-03
Tuesday26 messages6 participantstimes are UTC
Highlights from this day
- chlorhex — my 10 vial in 3ml gives 2.5mg/ml so 7.5 lands on 25 units, thats why i picked that volume, for what its worth 10:13
- chlorhex — SELECT was cardiovascular outcomes in people with overweight and existing disease, not a weight trial 10:25
- rae_labels — did anybody find a difference between SSA and pharmacy at the same 2 12:46
- rae_labels — i stayed on 1.7 for 24 months and never went to 2.4, appetite was already where i needed it 13:37
- rae_labels — follow up going slow cost me nothing except time and saved me two bad weeks, thats my whole contribution 13:51
does moving my dose day by two days matter with a seven day half life
STEP 1 ran to 68 weeks. thats the one everyone half remembers
for the archive was SURPASS-2 the one that ran to 68 weeks or am i mixing them up
if youre comparing brand to compounded, dose accuracy in the vial is the variable, not the molecule
my 10 vial in 3ml gives 2.5mg/ml so 7.5 lands on 25 units, thats why i picked that volume, for what its worth
[edited]SELECT was cardiovascular outcomes in people with overweight and existing disease, not a weight trial
held there too
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same dose day
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not the same trial
steady state takes weeks
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does the licensed ceiling for weight differ from the diabetes one
mine faded too
how did people handle the jump from 1 to 1.7
vial units and pen clicks are different systems, mixing the two is how people end up wrong
vials not pens here
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FLOW was the kidney outcomes trial and it gets quoted in here for things it didnt measure
STEP is several trials, so saying STEP said x is usually wrong without a number after it
did anybody find a difference between SSA and pharmacy at the same 2
back after 24 months off, do i restart at 0.25 or somewhere higher
genuine question im 12 months in at 12 and the appetite effect faded, is that a thing
*that should say weekly
i stayed on 1.7 for 24 months and never went to 2.4, appetite was already where i needed it
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brand vs compounded, is there a difference people can actually feel
follow up going slow cost me nothing except time and saved me two bad weeks, thats my whole contribution
thats STEP 1