the trials titrated on a fixed schedule, most people here dont, worth remembering when comparing
#semaglutide 2026-03-19
- LC_MS_Lena — update on the earlier thing the appetite effect faded for me around 5 months and going up fixed it for a while 20:08
- VialBot — Testing queue: 2 submissions open, 113 awaiting dispatch. 20:46
- LC_MS_Lena — coming back to this what did SELECT actually measure, i see it quoted for everything 21:04
- batch_bandit — im at 2 and stuck, did anyone break a plateau without going up 21:12
my 15 vial in 3ml gives 4mg/ml so 15 lands on 8 units, thats why i picked that volume
thats STEP 1
follow up changed my mind on the four week rule, i think it depends entirely on how the current dose feels
i held at 2.4 for 7 months and it was the best decision i made
went too fast once
| Trial schedule | What most people here do | |
|---|---|---|
| Step interval | 4 weeks, fixed | 4-12 weeks, on symptoms |
| Holding | protocol deviation | normal and expected |
| Top dose | reached by design | often never reached |
| Coming down | not studied | common at maintenance |
SELECT was cardiovascular outcomes in people with overweight and existing disease, not a weight trial
compounded and brand felt the same to me at 7.5, which is one person and nothing more
half life is about a week so youre roughly four to five weeks to steady state on any new dose
update on the earlier thing the appetite effect faded for me around 5 months and going up fixed it for a while
Testing queue: 2 submissions open, 113 awaiting dispatch.
coming back to this what did SELECT actually measure, i see it quoted for everything
give it four weeks
back after 26 months off, do i restart at 0.25 or somewhere higher
im at 2 and stuck, did anyone break a plateau without going up
i was wrong about the ceiling for a year, i thought 3 existed. it doesnt for the weight indication