i would use it
#storage-coldchain 2026-01-03
Saturday36 messages8 participantstimes are UTC
Highlights from this day
- rotate_the_site — lyophilised at room temp for 14 days in transit, worried or not 16:54
- fridge_thermo — light exposure matters much less than temperature for these. i still keep them in the carton 16:55
- auckland_aliquot — the practical risk in winter shipping is freezing, and in summer it is heat. plan for the season you are in 18:26
freeze thaw cycling is the risk, not one freeze. that is my read of it anyway
update from 25 months ago: replaced the fridge, temperature is stable, no more anxiety
a few hours at room temperature is almost certainly nothing. a week is a different conversation
i left a reconstituted vial out overnight once, sent it for testing out of curiosity, it came back fine
lyophilised at room temp for 14 days in transit, worried or not
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light exposure matters much less than temperature for these. i still keep them in the carton
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quick one a cooler with two gel packs held under eight degrees for eleven hours on a drive
unopened and in-use in the same place is fine. just keep the in-use one where you can reach it
power cut with the door shut for a few hours is fine. a full fridge holds temperature surprisingly well
anyone had a vial visibly change after a warm transit
the door swings four or five degrees every time somebody opens it. the back barely moves
if you are worried after a bad transit, test it. that is what the testing channels are for, ill dig out the number
i log the fridge temperature daily and the room has never let me forget it
freeze debate again
buy a thermometer. mine reads 4 on the door and two degrees lower at the back
does anyone freeze reconstituted vials or is that madness
the door swings four or five degrees every time somebody opens it. the back barely moves
the practical risk in winter shipping is freezing, and in summer it is heat. plan for the season you are in
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18:43chlorhex pinned a message
reconstituted solution is the fragile part. that is where the cold chain actually earns its keep
update from 7 months ago: replaced the fridge, temperature is stable, no more anxiety
i keep everything at the back of the middle shelf, never the door
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genuine question freezing reconstituted peptide is the one thing this channel has never agreed on, thats one data point
*that should say weekly
anyone tested a vial before and after a bad transit
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thats fine
for flying, hand luggage every time. the hold is not temperature controlled the way people assume
i freeze aliquots and have had them test fine afterwards. others here would not do it and i understand why
two to eight degrees. most domestic fridge doors are not in that range and people do not check
nobody here can tell you a vial is safe. we can tell you what has and has not survived for us, from memory
a few hours at room temperature is almost certainly nothing. a week is a different conversation
[edited]the vial that visibly changed after a warm transit was the one that had already been reconstituted
back of the fridge
i have never had a lyophilised vial fail after a warm transit and i have had some bad ones
the door swings four or five degrees every time somebody opens it. the back barely moves
hotel minibars are frequently not cold enough. i take a thermometer, which is ridiculous and also correct
right so do you keep the unopened vials and the in-use one in the same place
does the amber vial thing matter or is it marketing
[edited]for the archive lyophilised powder is genuinely robust. a warm transit is far less likely to matter than people fear