reconstituted solution is the fragile part. that is where the cold chain actually earns its keep
#storage-coldchain 2026-04-08
Wednesday24 messages5 participantstimes are UTC
Highlights from this day
- kev_measures — how cold is too cold, can it actually freeze in a normal fridge 20:23
- seizure_letter — freeze thaw cycling is the risk, not one freeze. that is my read of it anyway 20:25
- shame_and_meds — buy a thermometer. mine reads 4 on the door and two degrees lower at the back 20:39
- kev_measures — does the fridge in a hotel room count as a fridge 22:49
how cold is too cold, can it actually freeze in a normal fridge
mon 4.1 / door 7.2
tue 4.0 / door 7.8
wed 4.2 / door 6.9
thu 3.9 / door 7.4
fri 4.1 / door 8.1 <- shopping day
sat 4.3 / door 7.0
sun 4.0 / door 6.8for flying, hand luggage every time. the hold is not temperature controlled the way people assume
freeze thaw cycling is the risk, not one freeze. that is my read of it anyway
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i log the fridge temperature daily and the room has never let me forget it, i have it written down somewhere
lyophilised powder is genuinely robust. a warm transit is far less likely to matter than people fear
cold pack arrived completely liquid, does that mean anything
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buy a thermometer. mine reads 4 on the door and two degrees lower at the back
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two to eight
mon 4.1 / door 7.2
tue 4.0 / door 7.8
wed 4.2 / door 6.9
thu 3.9 / door 7.4
fri 4.1 / door 8.1 <- shopping day
sat 4.3 / door 7.0
sun 4.0 / door 6.8is there a difference in stability between the compounds
anyone had a vial visibly change after a warm transit
light exposure matters much less than temperature for these. i still keep them in the carton
test it
i left it out overnight by accident, bin it or use it
is a five pound fridge thermometer actually worth it
the vial that visibly changed after a warm transit was the one that had already been reconstituted
i would use it
mon 4.1 / door 7.2
tue 4.0 / door 7.8
wed 4.2 / door 6.9
thu 3.9 / door 7.4
fri 4.1 / door 8.1 <- shopping day
sat 4.3 / door 7.0
sun 4.0 / door 6.8anyone tested a vial before and after a bad transit
do you log the fridge temperature or is that too far
two to eight degrees. most domestic fridge doors are not in that range and people do not check
door shelf or back of the fridge
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i keep everything at the back of the middle shelf, never the door, from memory
does the fridge in a hotel room count as a fridge
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powder is robust