#tirzepatide 2024-01-13

Saturday15 messages4 participantstimes are UTC

Highlights from this day

batch_bandit — at 12 my appetite went completely and i dropped back a step, eating nothing isnt a win 00:33
logrotate — if youre coming off semaglutide the honest answer is start low and find out, theres no table, anyway 01:22
noct.titrate — is SURMOUNT-OSA the sleep apnoea one 12 did nothing extra over 10 for me and that still holds a year later 01:27
taper_tess — quick one the trials titrated every four weeks to a target, most people here stop at whatever works 02:25

is the sweet spot argument about effect or about side effects

did anybody switch back to semaglutide after trying this

at 12 my appetite went completely and i dropped back a step, eating nothing isnt a win

anyone tracked whether the GI difference held at the top doses

easier gi for me

start low anyway

✅17🧪5🔥6

right so £72 for a 20 vial is roughly what ive paid for the last year

if youre coming off semaglutide the honest answer is start low and find out, theres no table, anyway

5 did nothing

wk 1-4    2.5mg
wk 5-8    5.0mg
wk 9-20   7.5mg   <- stayed here
wk 21-24  10.0mg  (no extra benefit for me)
wk 25+    7.5mg   (came back down)

back after 10 months, do i restart at 2.5 or pick up near where i left off

is SURMOUNT-OSA the sleep apnoea one
12 did nothing extra over 10 for me and that still holds a year later

no clean conversion

does the GIP arm actually explain the easier nausea or is that hand waving

i argued the sweet spot was nonsense and then spent 14 months at 7.5 not needing more

quick one the trials titrated every four weeks to a target, most people here stop at whatever works