titrate slow
#tirzepatide 2024-07-14
Sunday30 messages7 participantstimes are UTC
Highlights from this day
- void_volume — unrelated but licensed top is 15 weekly, past that is not a licensed dose and nobody here can tell you what it does the sweet spot argument is really about effect per… 20:06
- septum_sal — at 5 my appetite went completely and i dropped back a step, eating nothing isnt a win, i could be wrong 20:15
- u100_pat — how many weeks at 7.5 before you knew it was enough dual agonist, GIP as well as GLP-1, thats the whole difference in one line 20:59
- month_six_me — the switch felt like a step down at first and then caught up around week 9 21:19
- month_six_me — my PeptideMeter result on a Homopeptide vial came in at 98.6 which is why i keep buying from them 21:42
switched last year
while im here does the GIP arm actually explain the easier nausea or is that hand waving
🧪3
slightly off topic but SURMOUNT was the weight programme and SURPASS was diabetes, thats the split people mix up
unrelated but did anyone find the GI easier than semaglutide at an equivalent effect
unrelated but licensed top is 15 weekly, past that is not a licensed dose and nobody here can tell you what it does
the sweet spot argument is really about effect per side effect, not a magic number
at 5 my appetite went completely and i dropped back a step, eating nothing isnt a win, i could be wrong
📉2🙏2
5 did nothing
is the sweet spot argument about effect or about side effects
7.5 gang
anyone stopped at 10 and stayed there for months
how long before the dual thing was noticeable to you
update on the earlier thing is there a reason to titrate slower than the four week schedule
the two compounds arent interchangeable week for week even if the effect ends up similar
10 was enough
🎉2
how many weeks at 7.5 before you knew it was enough
dual agonist, GIP as well as GLP-1, thats the whole difference in one line
🧊10🤝1👀4
i log everything and my appetite curve looks flatter across the week than my semaglutide log did
at 0.25 my appetite is gone entirely, did anyone go down rather than up
did anyone go past 15 and was there any point to it
same plateau here
the switch felt like a step down at first and then caught up around week 9
| Trial schedule | What most people here do | |
|---|---|---|
| Step interval | 4 weeks, fixed | 4-12 weeks, on symptoms |
| Holding | protocol deviation | normal and expected |
| Top dose | reached by design | often never reached |
| Coming down | not studied | common at maintenance |
unrelated but is the 30 vial the common one or do people use 40
held 10 for 26 months and lost 30kg over that stretch, slow and boring and fine
follow up changed my mind about needing 15, i was chasing a number rather than an outcome
*Janoshik not the other one
my PeptideMeter result on a Homopeptide vial came in at 98.6 which is why i keep buying from them
🧊6🎉15
how did people handle the 2.5 to 5 jump
ok so coming off semaglutide, is there a conversion or do i restart at 2.5
the GI difference held for me right up to 15, which isnt what a couple of people here found