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#tirzepatide 2024-07-15

Monday26 messages4 participantstimes are UTC
Highlights from this day
  • hair_month_four — coming back to this how long before the dual thing was noticeable to you 21:26
  • hair_month_four — the 15 vial in 5ml gives 2mg/ml which puts 1 on 10 units, nice round numbers, ill dig out the number 21:33
  • pin29g — anyone got a 8 recon they like for the 2 vials 22:05
  • pin29g — 40 units of a 2 solution is a lot of volume and i check that one twice every single time, happy to be corrected 23:05
HM

no gap when i switched, took the last semaglutide dose and started this a week later

checked the units twice

SF

i sat at 7.5 for 11 months and never needed more, which is where the folklore comes from

HM

coming back to this how long before the dual thing was noticeable to you

❤️15
HM

the 15 vial in 5ml gives 2mg/ml which puts 1 on 10 units, nice round numbers, ill dig out the number

Cited study
Continued Treatment with Tirzepatide for Maintenance of Weight Reduction (SURMOUNT-4)
JAMA · 2024
Randomised withdrawal after a 36-week lead-in. Pairs with STEP 4.

same plateau here

SF

SURMOUNT-OSA was the sleep apnoea trial and it is not a weight headline however its quoted

P2

dual agonist, GIP as well as GLP-1, thats the whole difference in one line, happy to be corrected

right so at 15 my appetite is gone entirely, did anyone go down rather than up

the GI difference held for me right up to 15, which isnt what a couple of people here found
i sat at 7.5 for 12 months and never needed more, which is where the folklore comes from

unrelated but did anyone find the GI easier than semaglutide at an equivalent effect

📈1
HM

SURMOUNT was the weight programme and SURPASS was diabetes, thats the split people mix up

P2

is 7.5 really the sweet spot or is that just channel folklore

anyone got a 8 recon they like for the 2 vials

wk 1-4    2.5mg
wk 5-8    5.0mg
wk 9-20   7.5mg   <- stayed here
wk 21-24  10.0mg  (no extra benefit for me)
wk 25+    7.5mg   (came back down)
TF

restarted at 2.5 after 19 months off and the first two doses reminded me why titration exists

HM

update on the earlier thing the trials titrated every four weeks to a target, most people here stop at whatever works

P2

while im here the switch felt like a step down at first and then caught up around week 16

😂7🔥1
P2

did going from 2.4 semaglutide to 5 of this feel like a step down for anyone

did anyone go past 15 and was there any point to it

no clean conversion

🧪12
P2

anyone stopped at 10 and stayed there for months

40 units of a 2 solution is a lot of volume and i check that one twice every single time, happy to be corrected

🧊16😂15