vialroom

#tirzepatide 2024-11-24

Sunday45 messages10 participantstimes are UTC
Highlights from this day
  • c18_column — how long before the dual thing was noticeable to you 19:29
  • salt_bridge — restarted at 2.5 after 10 months off and the first two doses reminded me why titration exists, i have it written down somewhere 20:21
  • tablet_tam — the 2 vial in 3ml gives 5mg/ml which puts 5 on 10 units, nice round numbers 21:03
  • noct.titrate — the sweet spot thing is survivorship, the people it worked for stayed and said so 21:16
  • factory_direct_fi — licensed top is 15 weekly, past that is not a licensed dose and nobody here can tell you what it does at 15 the GI came back for me, so my easier profile claim only… 22:20
TS

the GI difference held for me right up to 15, which isnt what a couple of people here found

at 15 the GI came back for me, so my easier profile claim only applies below that

AT

40 units of a 2.5 solution is a lot of volume and i check that one twice every single time

10 was enough

C1

how long before the dual thing was noticeable to you

👍5💀5❤️6

i argued the sweet spot was nonsense and then spent 16 months at 7.5 not needing more

👀6
LN

unrelated but the two compounds arent interchangeable week for week even if the effect ends up similar

did anyone find the GI easier than semaglutide at an equivalent effect
licensed top is 15 weekly, past that is not a licensed dose and nobody here can tell you what it does

C1

anyone tracked whether the GI difference held at the top doses

C1

how many weeks at 7.5 before you knew it was enough
the 10 vial in 1.5ml gives 2mg/ml which puts 2.4 on 50 units, nice round numbers

C1

the switch felt like a step down at first and then caught up around week 33

plateaued at 28 weeks the same way i did on semaglutide, so i doubt its compound specific

5 was where i first noticed it properly, 2.5 did almost nothing for me

at 2.4 my appetite is gone entirely, did anyone go down rather than up

FD

i log everything and my appetite curve looks flatter across the week than my semaglutide log did

SB

i sat at 7.5 for 5 months and never needed more, which is where the folklore comes from

anyone got a 2.5 recon they like for the 15 vials

restarted at 2.5 after 10 months off and the first two doses reminded me why titration exists, i have it written down somewhere

👀17

start low anyway

GI was noticeably easier for me than semaglutide at what felt like the same appetite effect

GIP plus GLP-1

👀6👍2

folklore probably

back after 1 months, do i restart at 2.5 or pick up near where i left off

NT

right so changed my mind about needing 15, i was chasing a number rather than an outcome, i have it written down somewhere

TT

the 2 vial in 3ml gives 5mg/ml which puts 5 on 10 units, nice round numbers

Cited study
Tirzepatide for Obstructive Sleep Apnea and Obesity (SURMOUNT-OSA)
New England Journal of Medicine · 2024
AHI as the primary endpoint, with and without PAP therapy.

SURMOUNT is weight

NT

the sweet spot thing is survivorship, the people it worked for stayed and said so

weights-monthly.csv
620 rows · not retained in the public archive
TT

is the sweet spot argument about effect or about side effects

OW

im at 1.7 and thinking about 10, did anyone gain anything from that step

TT

ok so held 10 for 20 months and lost 12kg over that stretch, slow and boring and fine

FD

licensed top is 15 weekly, past that is not a licensed dose and nobody here can tell you what it does
at 15 the GI came back for me, so my easier profile claim only applies below that

🤝1❤️16😂2