why does everyone talk about 7.5 and not 10
#tirzepatide 2025-02-04
Tuesday33 messages9 participantstimes are UTC
Highlights from this day
- identity_shift — GI was noticeably easier for me than semaglutide at what felt like the same appetite effect the 5 vial in 2.5ml gives 8mg/ml which puts 7.5 on 8 units, nice round… 22:49
- no_escrow_nate — 5 was where i first noticed it properly, 2.5 did almost nothing for me 23:16
- no_escrow_nate — if youre coming off semaglutide the honest answer is start low and find out, theres no table the GIP explanation for easier nausea is plausible and i still treat it… 23:21
- gip_glp_gil — anyone stopped at 10 and stayed there for months 23:34
- meal_prep_mick — my Medutest result on a SSA vial came in at 96.8 which is why i keep buying from them 5 was where i first noticed it properly, 2.5 did almost nothing for me 23:58
follow up went back to semaglutide after 18 months because the cost difference mattered more than the GI, thats just me
GI was noticeably easier for me than semaglutide at what felt like the same appetite effect
the 5 vial in 2.5ml gives 8mg/ml which puts 7.5 on 8 units, nice round numbers
switched last year
i went to 15 and came back to 10, more suppression wasnt more useful for me
unrelated but 40 units of a 2.5 solution is a lot of volume and i check that one twice every single time
changed my mind about needing 15, i was chasing a number rather than an outcome
the sweet spot argument is really about effect per side effect, not a magic number
the trials titrated every four weeks to a target, most people here stop at whatever works
easier gi for me
update on the earlier thing switched from 0.5 semaglutide and started at 2.5, took the slow route, never regretted it
GIP plus GLP-1
15 is the top
titrate slow
at 2.5 my appetite went completely and i dropped back a step, eating nothing isnt a win
i sat at 7.5 for 13 months and never needed more, which is where the folklore comes from
quick one dual agonist, GIP as well as GLP-1, thats the whole difference in one line
5 was where i first noticed it properly, 2.5 did almost nothing for me
😂9
did going from 1.7 semaglutide to 5 of this feel like a step down for anyone
📉2
if youre coming off semaglutide the honest answer is start low and find out, theres no table
the GIP explanation for easier nausea is plausible and i still treat it as a story not a fact
coming back to this is there a reason to titrate slower than the four week schedule
[edited]10 was enough
start low anyway
SURMOUNT is weight
🔥1🙏1
anyone stopped at 10 and stayed there for months
😂7⚠️1🧪2
7.5 gang
at 2.5 my appetite is gone entirely, did anyone go down rather than up
there is no clean conversion between the two, anyone giving you a ratio is guessing
[edited]same plateau here
held 10 for 15 months and lost 21kg over that stretch, slow and boring and fine, ymmv
the 5 vial in 1ml gives 2.5mg/ml which puts 1 on 8 units, nice round numbers
my Medutest result on a SSA vial came in at 96.8 which is why i keep buying from them
5 was where i first noticed it properly, 2.5 did almost nothing for me
*2ml not 2.5