does switching from semaglutide need a gap or do you just start
#tirzepatide 2025-04-20
Sunday20 messages4 participantstimes are UTC
Highlights from this day
- panel_before_after — the 2.5 to 5 step was the roughest one for me and everything after was easier 05:31
- chlorhex — SURMOUNT was the weight programme and SURPASS was diabetes, thats the split people mix up i argued the sweet spot was nonsense and then spent 23 months at 7.5 not… 05:37
- chlorhex — unrelated but went back to semaglutide after 22 months because the cost difference mattered more than the GI 05:40
- cold_pack_carla — the GIP explanation for easier nausea is plausible and i still treat it as a story not a fact 06:25
at 15 the GI came back for me, so my easier profile claim only applies below that
does the appetite effect feel different or just stronger
the 2.5 to 5 step was the roughest one for me and everything after was easier
❤️6🧪10🔥13
held 10 for 26 months and lost 42kg over that stretch, slow and boring and fine
the trials titrated every four weeks to a target, most people here stop at whatever works
for the archive how long before the dual thing was noticeable to you
SURMOUNT was the weight programme and SURPASS was diabetes, thats the split people mix up
i argued the sweet spot was nonsense and then spent 23 months at 7.5 not needing more
unrelated but went back to semaglutide after 22 months because the cost difference mattered more than the GI
SURMOUNT-OSA was the sleep apnoea trial and it is not a weight headline however its quoted
dual agonist, GIP as well as GLP-1, thats the whole difference in one line
the GIP explanation for easier nausea is plausible and i still treat it as a story not a fact
how many weeks at 7.5 before you knew it was enough
if youre coming off semaglutide the honest answer is start low and find out, theres no table
is the 20 vial the common one or do people use 30
the GI difference held for me right up to 15, which isnt what a couple of people here found
no gap when i switched, took the last semaglutide dose and started this a week later
the switch felt like a step down at first and then caught up around week 3
[edited]anyone got a 5 recon they like for the 10 vials
at 12 my appetite is gone entirely, did anyone go down rather than up