vialroom

#tirzepatide 2025-04-27

Sunday21 messages7 participantstimes are UTC
Highlights from this day
  • VialBot — Inter-lab diff for lot KP-0925: 98.1% vs 99%. Within expected range. 23:12
  • gradient_greg — coming off semaglutide, is there a conversion or do i restart at 2.5 23:34
  • spreadsheet_stu — i sat at 7.5 for 18 months and never needed more, which is where the folklore comes from 23:36
RT

changed my mind about needing 15, i was chasing a number rather than an outcome

RS

plateaued at 19 weeks the same way i did on semaglutide, so i doubt its compound specific

40 units of a 2.5 solution is a lot of volume and i check that one twice every single time

no clean conversion

MP

the sweet spot argument is really about effect per side effect, not a magic number

VB

Inter-lab diff for lot KP-0925: 98.1% vs 99%. Within expected range.

RS

for the archive the sweet spot thing is survivorship, the people it worked for stayed and said so

GG

i argued the sweet spot was nonsense and then spent 20 months at 7.5 not needing more

how many weeks at 7.5 before you knew it was enough

GG

is the 15 vial the common one or do people use 20
12 did nothing extra over 10 for me and that still holds a year later

at 15 the GI came back for me, so my easier profile claim only applies below that

12 did nothing extra over 10 for me and that still holds a year later

coming off semaglutide, is there a conversion or do i restart at 2.5

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23:35chlorhex pinned a message to this channel
SS

i sat at 7.5 for 18 months and never needed more, which is where the folklore comes from

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how long before the dual thing was noticeable to you

why does everyone talk about 7.5 and not 10

is there a reason to titrate slower than the four week schedule

CH

checked the units twice

Cited study
Tirzepatide for Obstructive Sleep Apnea and Obesity (SURMOUNT-OSA)
New England Journal of Medicine · 2024
AHI as the primary endpoint, with and without PAP therapy.
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