held 10 for 5 months and lost 10kg over that stretch, slow and boring and fine
#tirzepatide 2025-05-29
Thursday54 messages11 participantstimes are UTC
Highlights from this day
- quiet.hours — i sat at 7.5 for 24 months and never needed more, which is where the folklore comes from, i have it written down somewhere 10:45
- bengaluru_bac — licensed top is 15 weekly, past that is not a licensed dose and nobody here can tell you what it does 12:57
- baseline_drift — quick one anyone stopped at 10 and stayed there for months 14:10
- quiet.hours — at 2.5 my appetite went completely and i dropped back a step, eating nothing isnt a win 15:51
- two_lifts_a_week — SURMOUNT was the weight programme and SURPASS was diabetes, thats the split people mix up, from memory 16:03
i sat at 7.5 for 24 months and never needed more, which is where the folklore comes from, i have it written down somewhere
⚠️16
at 15 the GI came back for me, so my easier profile claim only applies below that
does the GIP arm actually explain the easier nausea or is that hand waving
10 was enough
i argued the sweet spot was nonsense and then spent 9 months at 7.5 not needing more
🧪8
is the 20 vial the common one or do people use 5
✅4
the two compounds arent interchangeable week for week even if the effect ends up similar
same plateau here
sorry to jump in the sweet spot argument is really about effect per side effect, not a magic number
unrelated but 12 did nothing extra over 10 for me and that still holds a year later
the GIP explanation for easier nausea is plausible and i still treat it as a story not a fact, your mileage will differ
💀4
the trials titrated every four weeks to a target, most people here stop at whatever works
at 15 the GI came back for me, so my easier profile claim only applies below that
7.5 gang
switched last year
5 was where i first noticed it properly, 2.5 did almost nothing for me
🙏2
quick one did anybody switch back to semaglutide after trying this
🎉15
my Janoshik result on a QYB vial came in at 99.4 which is why i keep buying from them
how did people handle the 2.5 to 5 jump
folklore probably
📈6📉2
changed my mind about needing 15, i was chasing a number rather than an outcome
fridge-temps.csv
93 rows · not retained in the public archive
titrate slow
no clean conversion
licensed top is 15 weekly, past that is not a licensed dose and nobody here can tell you what it does
😂10🙏17
no gap when i switched, took the last semaglutide dose and started this a week later
✅16
switched from 5 semaglutide and started at 2.5, took the slow route, never regretted it
slightly off topic but the GI difference held for me right up to 15, which isnt what a couple of people here found
anyone got a 4 recon they like for the 15 vials
licensed top is 15 weekly, past that is not a licensed dose and nobody here can tell you what it does
anyone tracked whether the GI difference held at the top doses
checked the units twice
there is no clean conversion between the two, anyone giving you a ratio is guessing
Purity check: no report on file for lot C-4402. Nothing logged either way.
quick one anyone stopped at 10 and stayed there for months
✅1🔥16
i went to 15 and came back to 10, more suppression wasnt more useful for me, for what its worth
12 did nothing extra over 10 for me and that still holds a year later
whats the plateau pattern here, same as semaglutide or different
SURMOUNT is weight
£55 for a 20 vial is roughly what ive paid for the last year
📉15
coming back to this restarted at 2.5 after 15 months off and the first two doses reminded me why titration exists
went back to semaglutide after 11 months because the cost difference mattered more than the GI
at 2.5 my appetite went completely and i dropped back a step, eating nothing isnt a win
✅1📉13🎉15
40 units of a 2.5 solution is a lot of volume and i check that one twice every single time
👀4
5 did nothing
easier gi for me
did anyone find the GI easier than semaglutide at an equivalent effect
SURMOUNT was the weight programme and SURPASS was diabetes, thats the split people mix up, from memory
🧊11🤝12🙏4
start low anyway
12 did nothing extra over 10 for me and that still holds a year later
🧊5
start low anyway
the GI difference held for me right up to 15, which isnt what a couple of people here found
😂7
15 is the top
Recon calculator: 15mg in 1ml = 10mg/ml.
GIP plus GLP-1
is there a reason to titrate slower than the four week schedule
the 40 vial in 1.5ml gives 5mg/ml which puts 12 on 12 units, nice round numbers