slightly off topic but plateaued at 21 weeks the same way i did on semaglutide, so i doubt its compound specific
🙏10📈4
#tirzepatide 2025-07-14
Monday33 messages7 participantstimes are UTC
Highlights from this day
- vialkeeper — quick one at 15 the GI came back for me, so my easier profile claim only applies below that 21:42
- freeze_thaw — GI was noticeably easier for me than semaglutide at what felt like the same appetite effect 22:11
- freeze_thaw — the GI difference held for me right up to 15, which isnt what a couple of people here found 23:05
the sweet spot argument is really about effect per side effect, not a magic number
the 2.5 to 5 step was the roughest one for me and everything after was easier
10 was enough
there is no clean conversion between the two, anyone giving you a ratio is guessing
whats the top licensed dose, 15 or does it go higher
whats the plateau pattern here, same as semaglutide or different
5 was where i first noticed it properly, 2.5 did almost nothing for me
the two compounds arent interchangeable week for week even if the effect ends up similar
5 did nothing
how many weeks at 7.5 before you knew it was enough
quick one at 15 the GI came back for me, so my easier profile claim only applies below that
| Trial schedule | What most people here do | |
|---|---|---|
| Step interval | 4 weeks, fixed | 4-12 weeks, on symptoms |
| Holding | protocol deviation | normal and expected |
| Top dose | reached by design | often never reached |
| Coming down | not studied | common at maintenance |
GIP plus GLP-1
follow up anyone stopped at 10 and stayed there for months
titrate slow
40 units of a 4 solution is a lot of volume and i check that one twice every single time
follow up is 7.5 really the sweet spot or is that just channel folklore
folklore probably
is the 40 vial the common one or do people use 20
did anybody switch back to semaglutide after trying this
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£72 for a 5 vial is roughly what ive paid for the last year
licensed top is 15 weekly, past that is not a licensed dose and nobody here can tell you what it does
GI was noticeably easier for me than semaglutide at what felt like the same appetite effect
🙏9🧊11
right so held 10 for 20 months and lost 7kg over that stretch, slow and boring and fine, ask me again in a month
✅1🧪2
no gap when i switched, took the last semaglutide dose and started this a week later
SURMOUNT is weight
👀6
SURMOUNT was the weight programme and SURPASS was diabetes, thats the split people mix up
back after 8 months, do i restart at 2.5 or pick up near where i left off
same plateau here
the switch felt like a step down at first and then caught up around week 7
start low anyway
the GI difference held for me right up to 15, which isnt what a couple of people here found
wk 1-4 2.5mg
wk 5-8 5.0mg
wk 9-20 7.5mg <- stayed here
wk 21-24 10.0mg (no extra benefit for me)
wk 25+ 7.5mg (came back down)