vialroom

#tirzepatide 2025-08-08

Friday20 messages4 participantstimes are UTC
Highlights from this day
  • cold_chain_cmdr — i log everything and my appetite curve looks flatter across the week than my semaglutide log did, ill dig out the number 22:43
  • group_buy_gwen — did going from 1 semaglutide to 5 of this feel like a step down for anyone 22:59
  • verify_or_dont — held 10 for 15 months and lost 10kg over that stretch, slow and boring and fine 23:06
  • manila_meniscus — unrelated but there is no clean conversion between the two, anyone giving you a ratio is guessing 23:40
  • group_buy_gwen — my Medutest result on a WWB vial came in at 98.1 which is why i keep buying from them 23:43

12 did nothing extra over 10 for me and that still holds a year later

MM

coming back to this the sweet spot thing is survivorship, the people it worked for stayed and said so, i could be wrong

*Janoshik not the other one

15 is the top

titrate slow

CC

i log everything and my appetite curve looks flatter across the week than my semaglutide log did, ill dig out the number

GB

did going from 1 semaglutide to 5 of this feel like a step down for anyone

❤️17🔥14👀11

GI was noticeably easier for me than semaglutide at what felt like the same appetite effect

VO

held 10 for 15 months and lost 10kg over that stretch, slow and boring and fine

Cited study
Tirzepatide Once Weekly for the Treatment of Obesity (SURMOUNT-1)
New England Journal of Medicine · 2022
72 weeks, tirzepatide 5, 10 and 15mg against placebo.

i went to 15 and came back to 10, more suppression wasnt more useful for me

GIP plus GLP-1

MM

unrelated but there is no clean conversion between the two, anyone giving you a ratio is guessing

wk 1-4    2.5mg
wk 5-8    5.0mg
wk 9-20   7.5mg   <- stayed here
wk 21-24  10.0mg  (no extra benefit for me)
wk 25+    7.5mg   (came back down)
GB

my Medutest result on a WWB vial came in at 98.1 which is why i keep buying from them