checked the units twice
#tirzepatide 2025-09-08
Monday34 messages6 participantstimes are UTC
Highlights from this day
- swab_dry_first — the 15 vial in 1ml gives 5mg/ml which puts 1 on 30 units, nice round numbers 19:22
- customs_owl — im at 0.25 and thinking about 2.5, did anyone gain anything from that step 19:50
- tokyo_taper — while im here back after 2 months, do i restart at 2.5 or pick up near where i left off 20:52
- forty_five_kg — did going from 12 semaglutide to 5 of this feel like a step down for anyone 22:58
- forty_five_kg — the trials titrated every four weeks to a target, most people here stop at whatever works GI was noticeably easier for me than semaglutide at what felt like the same… 23:22
*VendorInvestigate not the other one
GIP plus GLP-1
40 units of a 2 solution is a lot of volume and i check that one twice every single time
licensed top is 15 weekly, past that is not a licensed dose and nobody here can tell you what it does
ok so anyone stopped at 10 and stayed there for months
while im here at 1.7 my appetite went completely and i dropped back a step, eating nothing isnt a win
the 15 vial in 1ml gives 5mg/ml which puts 1 on 30 units, nice round numbers
🎉12
easier gi for me
switched last year
the two compounds arent interchangeable week for week even if the effect ends up similar, n of 1 obviously
the sweet spot thing is survivorship, the people it worked for stayed and said so
coming back to this i sat at 7.5 for 21 months and never needed more, which is where the folklore comes from, your mileage will differ
im at 0.25 and thinking about 2.5, did anyone gain anything from that step
went back to semaglutide after 19 months because the cost difference mattered more than the GI, ill dig out the number
7.5 gang
the 2.5 to 5 step was the roughest one for me and everything after was easier
plateaued at 29 weeks the same way i did on semaglutide, so i doubt its compound specific
i went to 15 and came back to 10, more suppression wasnt more useful for me
[edited]no gap when i switched, took the last semaglutide dose and started this a week later
my VendorInvestigate result on a Homopeptide vial came in at 99.2 which is why i keep buying from them
titrate slow
🎉1📈1
while im here back after 2 months, do i restart at 2.5 or pick up near where i left off
| Trial schedule | What most people here do | |
|---|---|---|
| Step interval | 4 weeks, fixed | 4-12 weeks, on symptoms |
| Holding | protocol deviation | normal and expected |
| Top dose | reached by design | often never reached |
| Coming down | not studied | common at maintenance |
SURMOUNT is weight
folklore probably
12 did nothing extra over 10 for me and that still holds a year later
unrelated but the GIP explanation for easier nausea is plausible and i still treat it as a story not a fact
for the archive i log everything and my appetite curve looks flatter across the week than my semaglutide log did
held 10 for 22 months and lost 45kg over that stretch, slow and boring and fine
right so whats the top licensed dose, 15 or does it go higher
restarted at 2.5 after 17 months off and the first two doses reminded me why titration exists
at 15 the GI came back for me, so my easier profile claim only applies below that
there is no clean conversion between the two, anyone giving you a ratio is guessing
i argued the sweet spot was nonsense and then spent 8 months at 7.5 not needing more
did going from 12 semaglutide to 5 of this feel like a step down for anyone
🔥2👍12
the trials titrated every four weeks to a target, most people here stop at whatever works
GI was noticeably easier for me than semaglutide at what felt like the same appetite effect