my Medutest result on a SSA vial came in at 99.4 which is why i keep buying from them
#tirzepatide 2025-10-28
Tuesday49 messages13 participantstimes are UTC
Highlights from this day
*VendorInvestigate not the other one
€55 for a 15 vial is roughly what ive paid for the last year
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does switching from semaglutide need a gap or do you just start
how long before the dual thing was noticeable to you
switched from 12 semaglutide and started at 2.5, took the slow route, never regretted it, ymmv
wk 1-4 2.5mg
wk 5-8 5.0mg
wk 9-20 7.5mg <- stayed here
wk 21-24 10.0mg (no extra benefit for me)
wk 25+ 7.5mg (came back down)the GIP explanation for easier nausea is plausible and i still treat it as a story not a fact
Digest for the week of 2025-04-22 has been published.
if youre coming off semaglutide the honest answer is start low and find out, theres no table
start low anyway
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SURMOUNT was the weight programme and SURPASS was diabetes, thats the split people mix up, thats one data point
unrelated but 12 did nothing extra over 10 for me and that still holds a year later
is the 2 vial the common one or do people use 20
plateaued at 16 weeks the same way i did on semaglutide, so i doubt its compound specific
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is SURMOUNT-OSA the sleep apnoea one
wk 1-4 2.5mg
wk 5-8 5.0mg
wk 9-20 7.5mg <- stayed here
wk 21-24 10.0mg (no extra benefit for me)
wk 25+ 7.5mg (came back down)anyone got a 8 recon they like for the 30 vials
the sweet spot thing is survivorship, the people it worked for stayed and said so
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does the appetite effect feel different or just stronger
titrate slow
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no clean conversion
at 10 my appetite went completely and i dropped back a step, eating nothing isnt a win, from memory
the GI difference held for me right up to 15, which isnt what a couple of people here found
10 was enough
held 10 for 5 months and lost 13kg over that stretch, slow and boring and fine, thats one data point
how many weeks at 7.5 before you knew it was enough
did going from 1.7 semaglutide to 5 of this feel like a step down for anyone
GIP plus GLP-1
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15 is the top
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anyone tracked whether the GI difference held at the top doses
5 did nothing
GI was noticeably easier for me than semaglutide at what felt like the same appetite effect
how did people handle the 2.5 to 5 jump
the GI difference held for me right up to 15, which isnt what a couple of people here found
is there a reason to titrate slower than the four week schedule
slightly off topic but restarted at 2.5 after 8 months off and the first two doses reminded me why titration exists
folklore probably
same plateau here
changed my mind about needing 15, i was chasing a number rather than an outcome
i argued the sweet spot was nonsense and then spent 4 months at 7.5 not needing more
licensed top is 15 weekly, past that is not a licensed dose and nobody here can tell you what it does
coming back to this plateaued at 33 weeks the same way i did on semaglutide, so i doubt its compound specific, happy to be corrected
whats the plateau pattern here, same as semaglutide or different
[edited]at 15 the GI came back for me, so my easier profile claim only applies below that
coming off semaglutide, is there a conversion or do i restart at 2.5
*2ml not 2.5
checked the units twice
weights-monthly.csv
740 rows · not retained in the public archive
7.5 gang
i log everything and my appetite curve looks flatter across the week than my semaglutide log did, your mileage will differ
easier gi for me
did anybody switch back to semaglutide after trying this
the sweet spot argument is really about effect per side effect, not a magic number
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