vialroom

#tirzepatide 2025-12-09

Tuesday25 messages7 participantstimes are UTC
Highlights from this day
  • dana_titrates — coming back to this the switch felt like a step down at first and then caught up around week 32 19:16
  • patent_2026 — ok so the GI difference held for me right up to 15, which isnt what a couple of people here found 19:28
  • VialBot — New independent result logged — BCH, lot A-2418, purity 99% (VendorInvestigate). 19:52
  • patent_2026 — unrelated but the GIP explanation for easier nausea is plausible and i still treat it as a story not a fact the GIP explanation for easier nausea is plausible and i… 20:37
  • bpc_sceptic — coming back to this if youre coming off semaglutide the honest answer is start low and find out, theres no table, thats one data point 20:57
DT

coming back to this the switch felt like a step down at first and then caught up around week 32

🙏21
P2

ok so the GI difference held for me right up to 15, which isnt what a couple of people here found

🧪1📈12
DT

the 15 vial in 1ml gives 2.5mg/ml which puts 2.5 on 12 units, nice round numbers

VB

New independent result logged — BCH, lot A-2418, purity 99% (VendorInvestigate).

🧪7🎉1
P2

12 did nothing extra over 10 for me and that still holds a year later

while im here went back to semaglutide after 21 months because the cost difference mattered more than the GI, i think

P2

genuine question the trials titrated every four weeks to a target, most people here stop at whatever works

DT

plateaued at 24 weeks the same way i did on semaglutide, so i doubt its compound specific

P2

unrelated but the GIP explanation for easier nausea is plausible and i still treat it as a story not a fact
the GIP explanation for easier nausea is plausible and i still treat it as a story not a fact

💀1👀14👍7
LL

the 2.5 to 5 step was the roughest one for me and everything after was easier

BS

restarted at 2.5 after 26 months off and the first two doses reminded me why titration exists

LL

GI was noticeably easier for me than semaglutide at what felt like the same appetite effect

BS

coming back to this if youre coming off semaglutide the honest answer is start low and find out, theres no table, thats one data point

📉1
LL

genuine question SURMOUNT-1 versus SURPASS-2, which one was the weight trial

LL

did anyone find the GI easier than semaglutide at an equivalent effect

switched from 10 semaglutide and started at 2.5, took the slow route, never regretted it

*VendorInvestigate not the other one

is SURMOUNT-OSA the sleep apnoea one

*Medutest not the other one