is SURMOUNT-OSA the sleep apnoea one
#tirzepatide 2026-05-04
Monday35 messages8 participantstimes are UTC
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i sat at 7.5 for 9 months and never needed more, which is where the folklore comes from
lot-log.csv
287 rows · not retained in the public archive
my Medutest result on a GL Biochem vial came in at 97.4 which is why i keep buying from them
15:25marrow.mod pinned a message to this channel
the trials titrated every four weeks to a target, most people here stop at whatever works
GIP plus GLP-1
folklore probably
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same plateau here
start low anyway
titrate slow
how long before the dual thing was noticeable to you
the sweet spot thing is survivorship, the people it worked for stayed and said so
while im here the 10 vial in 2ml gives 5mg/ml which puts 2.5 on 20 units, nice round numbers
the sweet spot argument is really about effect per side effect, not a magic number, take that with a pinch of salt
SURMOUNT is weight
how many weeks at 7.5 before you knew it was enough
[edited]no_appetite_niawhile im here the 10 vial in 2ml gives 5mg/ml which puts 2.5 on 20 units, nice round…
does switching from semaglutide need a gap or do you just start
the two compounds arent interchangeable week for week even if the effect ends up similar
update on the earlier thing 5 was where i first noticed it properly, 2.5 did almost nothing for me
update on the earlier thing anyone tracked whether the GI difference held at the top doses
i went to 15 and came back to 10, more suppression wasnt more useful for me
im at 12 and thinking about 0.5, did anyone gain anything from that step
checked the units twice
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changed my mind about needing 15, i was chasing a number rather than an outcome
[edited]the 2.5 to 5 step was the roughest one for me and everything after was easier
the switch felt like a step down at first and then caught up around week 31
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whats the plateau pattern here, same as semaglutide or different
there is no clean conversion between the two, anyone giving you a ratio is guessing
17:28marrow.mod pinned a message to this channel
SURMOUNT-OSA was the sleep apnoea trial and it is not a weight headline however its quoted
the 2.5 to 5 step was the roughest one for me and everything after was easier
at 15 the GI came back for me, so my easier profile claim only applies below that
Inter-lab diff for lot F-1330: 98.6% vs 99.2%. Within expected range.
i argued the sweet spot was nonsense and then spent 17 months at 7.5 not needing more
10 was enough
did going from 2.4 semaglutide to 5 of this feel like a step down for anyone