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#tirzepatide 2026-05-25

Monday27 messages6 participantstimes are UTC
Highlights from this day
  • dana_titrates — at 0.25 my appetite went completely and i dropped back a step, eating nothing isnt a win 22:28
  • manila_meniscus — if youre coming off semaglutide the honest answer is start low and find out, theres no table, ill dig out the number 22:38
  • noct.titrate — SURMOUNT was the weight programme and SURPASS was diabetes, thats the split people mix up 5 was where i first noticed it properly, 2.5 did almost nothing for me 22:50
  • chlorhex — follow up 5 was where i first noticed it properly, 2.5 did almost nothing for me the trials titrated every four weeks to a target, most people here stop at whatever… 23:12

7.5 gang

ST

changed my mind about needing 15, i was chasing a number rather than an outcome

whats the top licensed dose, 15 or does it go higher

DT

did going from 2.5 semaglutide to 5 of this feel like a step down for anyone

does the appetite effect feel different or just stronger

DT

at 0.25 my appetite went completely and i dropped back a step, eating nothing isnt a win

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MM

the trials titrated every four weeks to a target, most people here stop at whatever works

NT

the sweet spot thing is survivorship, the people it worked for stayed and said so

SURMOUNT was the weight programme and SURPASS was diabetes, thats the split people mix up
5 was where i first noticed it properly, 2.5 did almost nothing for me

does switching from semaglutide need a gap or do you just start

CH

i argued the sweet spot was nonsense and then spent 1 months at 7.5 not needing more, someone check my working

follow up 40 units of a 10 solution is a lot of volume and i check that one twice every single time

GIP plus GLP-1

NT

does the GIP arm actually explain the easier nausea or is that hand waving

CH

follow up 5 was where i first noticed it properly, 2.5 did almost nothing for me
the trials titrated every four weeks to a target, most people here stop at whatever works

🎉1
ST

coming off semaglutide, is there a conversion or do i restart at 2.5

[edited]

no clean conversion

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