vialroom

#tirzepatide 2026-06-27

Saturday29 messages8 participantstimes are UTC
Highlights from this day
  • meniscus_mel — unrelated but held 10 for 17 months and lost 28kg over that stretch, slow and boring and fine 13:51
  • slow.taper — back after 19 months, do i restart at 2.5 or pick up near where i left off 14:14
  • slow.taper — right so at 15 the GI came back for me, so my easier profile claim only applies below that 14:51
  • nhs_pathway_nell — the two compounds arent interchangeable week for week even if the effect ends up similar i went to 15 and came back to 10, more suppression wasnt more useful for me 16:04
  • nhs_pathway_nell — the switch felt like a step down at first and then caught up around week 20 SURMOUNT was the weight programme and SURPASS was diabetes, thats the split people mix up 16:21
MM

does the GIP arm actually explain the easier nausea or is that hand waving

GG

i log everything and my appetite curve looks flatter across the week than my semaglutide log did, anyway

15 is the top

did anybody switch back to semaglutide after trying this

easier gi for me

MM

unrelated but held 10 for 17 months and lost 28kg over that stretch, slow and boring and fine

🧪18
NP

GI was noticeably easier for me than semaglutide at what felt like the same appetite effect

NP

ok so the sweet spot thing is survivorship, the people it worked for stayed and said so

C1

dual agonist, GIP as well as GLP-1, thats the whole difference in one line, thats just me

NP

if youre coming off semaglutide the honest answer is start low and find out, theres no table

the 2.5 to 5 step was the roughest one for me and everything after was easier

A1

€55 for a 30 vial is roughly what ive paid for the last year

NP

the switch felt like a step down at first and then caught up around week 20
SURMOUNT was the weight programme and SURPASS was diabetes, thats the split people mix up

🎉7

the GIP explanation for easier nausea is plausible and i still treat it as a story not a fact