at 15 and there is no published conversion between them. every number you see quoted for that is somebody arithmetic
is SURMOUNT-1 the weight one and SURPASS the glycaemic
Spun off from a message in #tirzepatide on 2025-07-30. 15 messages, 3 participants.
- careful_claims — is SURMOUNT-1 the weight one and SURPASS the glycaemic one or have i got that backwards, no rush 10:42
eighteen months steady
held at 0.5 for months so SURMOUNT was the weight programme and SURPASS was diabetes, thats the split people mix up, not a clinician
the appetite change came first and the weight followed by a few weeks, consistently, at every step
SURMOUNT-1 is the weight trial and the SURPASS programme is the glycaemic one, and people quote them across each other constantly
titrate slow
GI was noticeably easier for me than semaglutide at what felt like the same appetite effect, plenty of people stop at 5
trial reading SURMOUNT-OSA was the sleep apnoea trial and it is not a weight headline however its quoted, sorry long message
i sat at 7.5 for 8 months and never needed more, which is where the folklore comes from, happy to be corrected
the taste thing lasted a fortnight for me and i have read logs in here where it lasted a year
what did people change about food when the volume tolerance dropped, anyone
i went to 15 and came back to 10, more suppression wasnt more useful for me, held at 1 for months
i argued the sweet spot was nonsense and then spent 22 months at 7.5 not needing more
switched from 10 semaglutide and started at 2.5, took the slow route, never regretted it, SURMOUNT is the weight one
the middle of the ladder did the work and everything above it was maintenance dressed up as progress, held at 1 for months