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Thread · #tirzepatide · 2025-12-12

12 did nothing extra over 10 for me and

Spun off from a message in #tirzepatide on 2025-12-12. 17 messages, 5 participants.

The message this came from
  • question_queue — 12 did nothing extra over 10 for me and that still holds a year later 14:45

no clean conversion

QQ

SURMOUNT-OSA was the sleep apnoea trial and it is not a weight headline however its quoted

MP

at 2.4 my appetite went completely and i dropped back a step, eating nothing isnt a win

MP

went back to semaglutide after 12 months because the cost difference mattered more than the GI

NS

the GIP explanation for easier nausea is plausible and i still treat it as a story not a fact

QQ

dual agonist, GIP as well as GLP-1, thats the whole difference in one line

PS

40 units of a 5 solution is a lot of volume and i check that one twice every single time

MP

SURMOUNT-OSA was the sleep apnoea trial and it is not a weight headline however its quoted

🤝12
NS

the sweet spot thing is survivorship, the people it worked for stayed and said so