SURMOUNT was the weight programme and SURPASS was diabetes, thats the split people mix up, plenty of people stop at 5
Thread · #tirzepatide · 2026-03-25
is SURMOUNT-1 the weight one and SURPASS the glycaemic
Spun off from a message in #tirzepatide on 2026-03-25. 12 messages, 4 participants.
The message this came from
- turnaround_tam — dual agonist question is SURMOUNT-1 the weight one and SURPASS the glycaemic one or have i got that backwards 13:54
my notes across the switch are more useful than anything i remember about it, which is the argument for notes, that is somebody arithmetic, not data
the 2.5 step is a run in and the trials treat it that way. it is not expected to do much on its own
nothing above the licensed top has a published number attached to it, and this channel should keep saying so, hold if it is working
hope it sorts itself, four weeks a step
SURMOUNT-1 is the weight trial and the SURPASS programme is the glycaemic one, and people quote them across each other constantly, held at 2 for months
GI was noticeably easier for me than semaglutide at what felt like the same appetite effect, the population was studied properly
small correction to my earlier message the trials that pushed to the top doses were measuring what the top doses could do, not what you should take
not a prescriber but i held at 10 for eleven months and my clinician was entirely relaxed about it, four weeks at the step first
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is SURMOUNT a weight trial and SURPASS a glycaemic one, or have i got that backwards
held 10 for 5 months and lost 22kg over that stretch, slow and boring and fine, that is somebody arithmetic, not data
dexa results in coming from the other one, my first four weeks here were much easier than my first four weeks there, the middle did more for me