Topic
Degradants
Page 11 of 13 — Deamidation at plus one dalton, oxidation at plus sixteen, truncation sequences, and what a warm transit actually does.
Messages — page 11 of 13
HPLC_Hankplus 0.98 is deamidation#hplc-massspec · 2026-05-03HPLC_Hankplus 16 is oxidation#hplc-massspec · 2026-05-03marrow.modwhile im here deamidation is about plus 0.98 Da. it is not a rounding error, it is a degradant#hplc-massspec · 2026-05-03marrow.moda warm transit can put a visible degradant peak on a chromatogram. that is what 4 days at ambient does, thats one data point#hplc-massspec · 2026-05-03bench_notesoxidation is about plus 15.99 Da and is usually methionine or tryptophan#hplc-massspec · 2026-05-03dublin_dosea warm transit can put a visible degradant peak on a chromatogram. that is what 13 days at ambient does#hplc-massspec · 2026-05-04blank_runhow would a truncation sequence show up#hplc-massspec · 2026-05-06ferrous_ashplus 0.98 is deamidation#hplc-massspec · 2026-05-06careful_claimsa warm transit can put a visible degradant peak on a chromatogram. that is what 17 days at ambient does#hplc-massspec · 2026-05-06kelp_keepsoxidation is about plus 15.99 Da and is usually methionine or tryptophan#hplc-massspec · 2026-05-06monoisotopicplus 16 is oxidation#hplc-massspec · 2026-05-06kelp_keepstruncations show as a mass deficit matching one or more residues. you need the sequence to say which, thats one data point#hplc-massspec · 2026-05-06nordic_price_nilsdeamidation is about plus 0.98 Da. it is not a rounding error, it is a degradant two labs a point or two apart on the same lot…#hplc-massspec · 2026-05-07nordic_price_nilsplus 0.98 is deamidation#hplc-massspec · 2026-05-07nordic_price_nilsa warm transit can put a visible degradant peak on a chromatogram. that is what 21 days at ambient does#hplc-massspec · 2026-05-07LC_MS_Lenaoxidation is about plus 15.99 Da and is usually methionine or tryptophan#hplc-massspec · 2026-05-07LC_MS_Lenaa warm transit can put a visible degradant peak on a chromatogram. that is what 5 days at ambient does#hplc-massspec · 2026-05-08peak_splitplus 0.98 is deamidation#hplc-massspec · 2026-05-08pinch_not_stretchoxidation is about plus 15.99 Da and is usually methionine or tryptophan#hplc-massspec · 2026-05-09auckland_aliquottruncations show as a mass deficit matching one or more residues. you need the sequence to say which, ill dig out the number#hplc-massspec · 2026-05-10juno_joinsright so how would a truncation sequence show up#hplc-massspec · 2026-05-10juno_joinsplus 16 is oxidation#hplc-massspec · 2026-05-10brisbane_bacslightly off topic but plus sixteen, is that always oxidation#hplc-massspec · 2026-05-10lead_time_larsa warm transit can put a visible degradant peak on a chromatogram. that is what 15 days at ambient does#hplc-massspec · 2026-05-10forty_five_kgoxidation is about plus 15.99 Da and is usually methionine or tryptophan, i have it written down somewhere#hplc-massspec · 2026-05-10tail_factorplus 0.98 is deamidation#hplc-massspec · 2026-05-10ms_ms_miradeamidation is about plus 0.98 Da. it is not a rounding error, it is a degradant#hplc-massspec · 2026-05-11monoisotopicplus 0.98 is deamidation#hplc-massspec · 2026-05-12two_four_ceilingtruncations show as a mass deficit matching one or more residues. you need the sequence to say which#hplc-massspec · 2026-05-12dark_for_ten_daysplus sixteen, is that always oxidation#hplc-massspec · 2026-05-12gip_glp_gildeamidation is about plus 0.98 Da. it is not a rounding error, it is a degradant#hplc-massspec · 2026-05-12gip_glp_giloxidation is about plus 15.99 Da and is usually methionine or tryptophan#hplc-massspec · 2026-05-12two_four_ceilinghow would a truncation sequence show up#hplc-massspec · 2026-05-12HPLC_Hankhow would a truncation sequence show up#hplc-massspec · 2026-05-13still_here_2024plus 16 is oxidation#hplc-massspec · 2026-05-13still_here_2024deamidation is about plus 0.98 Da. it is not a rounding error, it is a degradant#hplc-massspec · 2026-05-13deamidationtruncations show as a mass deficit matching one or more residues. you need the sequence to say which#hplc-massspec · 2026-05-13deamidationplus 0.98 is deamidation#hplc-massspec · 2026-05-13still_here_2024a warm transit can put a visible degradant peak on a chromatogram. that is what 13 days at ambient does#hplc-massspec · 2026-05-13VialBotArchive lookup: truncation_tru first appears in this channel on 2026-01-18.#maintenance · 2026-05-13deamidationplus 0.98 is deamidation#hplc-massspec · 2026-05-14deamidationquick one deamidation is about plus 0.98 Da. it is not a rounding error, it is a degradant#hplc-massspec · 2026-05-14baseline_driftoxidation is about plus 15.99 Da and is usually methionine or tryptophan#hplc-massspec · 2026-05-14marrow.modslightly off topic but a warm transit can put a visible degradant peak on a chromatogram. that is what 12 days at ambient does#hplc-massspec · 2026-05-14void_volumetruncations show as a mass deficit matching one or more residues. you need the sequence to say which#hplc-massspec · 2026-05-15elder_eusorry to jump in deamidation is about plus 0.98 Da. it is not a rounding error, it is a degradant#hplc-massspec · 2026-05-15salt_bridgedeamidation is about plus 0.98 Da. it is not a rounding error, it is a degradant#hplc-massspec · 2026-05-16marrow.modthat is the main delivery route now. paid placement above the real result, on a mobile screen where the domain is truncated#scam-watch · 2026-05-16lyophile_livoxidation is about plus 15.99 Da and is usually methionine or tryptophan#hplc-massspec · 2026-05-17lyophile_livhow would a truncation sequence show up#hplc-massspec · 2026-05-17dana_titratesa warm transit can put a visible degradant peak on a chromatogram. that is what 21 days at ambient does#hplc-massspec · 2026-05-18dana_titratesright so plus sixteen, is that always oxidation#hplc-massspec · 2026-05-18karl_fischertruncations show as a mass deficit matching one or more residues. you need the sequence to say which#hplc-massspec · 2026-05-18deamidationplus 16 is oxidation#hplc-massspec · 2026-05-18willow_waitsoxidation is about plus 15.99 Da and is usually methionine or tryptophan#hplc-massspec · 2026-05-18tail_factorplus 0.98 is deamidation#hplc-massspec · 2026-05-18karl_fischercoming back to this deamidation is about plus 0.98 Da. it is not a rounding error, it is a degradant#hplc-massspec · 2026-05-18deamidationhow would a truncation sequence show up#hplc-massspec · 2026-05-18HPLC_Hankdeamidation is about plus 0.98 Da. it is not a rounding error, it is a degradant#hplc-massspec · 2026-05-19HPLC_Hankoxidation is about plus 15.99 Da and is usually methionine or tryptophan, i have it written down somewhere#hplc-massspec · 2026-05-19