vialroom

#cagrilintide 2026-02-22

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Highlights from this day
  • VialBot — On this day 9 years ago this channel logged 42 messages. 17:55
  • apob_over_ldl — monotherapy was underwhelming for me and i say that as someone who wanted it to work, still working it out weekly for me, same day every week, no reason beyond habit 20:01
  • apob_over_ldl — slightly off topic but if youre used to GLP-1 titration steps this feels absurdly cautious and i still do it that way, n of 1 obviously 20:03
TL

for the archive nobody should copy my schedule, im describing it because people asked what a slow ramp looks like

thats the phase 3 one

40 in 2ml gives 2.5mg/ml which is what i use, purely because the units come out round

IS

dropped the GLP-1 and stayed on this alone for 17 months, appetite held but weight barely moved

has REDEFINE reported or are people quoting earlier work

TL

combination GI was worse than either alone for me, which is not what i had read anywhere, thats just me

VB

On this day 9 years ago this channel logged 42 messages.

18
AO

coming back to this stopped for 15 months and the fullness went within a fortnight of the last dose

AO

i keep the two on separate days so if something goes wrong i have a chance of knowing which

NP

noticed something around week 23 on monotherapy, well after i had given up expecting to

AO

the combination is the thing with trial data behind it, monotherapy in here is mostly us guessing

AO

monotherapy was underwhelming for me and i say that as someone who wanted it to work, still working it out
weekly for me, same day every week, no reason beyond habit

slightly off topic but if youre used to GLP-1 titration steps this feels absurdly cautious and i still do it that way, n of 1 obviously

🧊16🤝12👍2

underwhelming honestly

held mine a while

did anyone add this to an existing retatrutide dose rather than starting both

RT

went slower because the first step gave me two rough days and i took that as information