vialroom

#dosing-titration 2024-11-11

Monday12 messages3 participantstimes are UTC
Highlights from this day
  • mg_per_ml — unrelated but anyone tracked whether a smaller more frequent dose changed their side effects 20:46
  • mag_citrate — the trials escalated on a fixed schedule because a trial has to. you are not a trial 21:37
  • pin29g — appetite returning at the end of the week is extremely common and is not the dose failing 21:38
MC

update from 3 months ago: held at the same dose the whole time and still losing slowly

MC

thats normal

Cited study
Tirzepatide Once Weekly for the Treatment of Obesity (SURMOUNT-1)
New England Journal of Medicine · 2022
72 weeks, tirzepatide 5, 10 and 15mg against placebo.
🎉5
MP

nobody here can tell you what dose to be on and the ones who try get corrected

is it normal for appetite to come back at the end of the week

MC

if it "stopped working after four days" that is almost never pharmacokinetics, ymmv

MP

unrelated but anyone tracked whether a smaller more frequent dose changed their side effects

MC

follow up coming down from 2.4 to 0.25, how bad is the appetite rebound

the trials escalated on a fixed schedule because a trial has to. you are not a trial

😂1
P2

appetite returning at the end of the week is extremely common and is not the dose failing