thats noise
#dosing-titration 2024-11-14
Thursday37 messages9 participantstimes are UTC
Highlights from this day
- seven_five_sweet — unrelated but is there a point where going up stops buying you anything the people who do best here are almost always the ones going slowest 12:12
- ferrous_ash — is week 32 too early to be thinking about the next step 14:48
- seven_five_sweet — how much does the last dose still matter 8 days later 14:49
- non_scale_win — dose day drift is mostly harmless with a weekly compound, but pick a day and defend it 16:34
- plus_sixteen — my titration ladder took 8 months to climb and i would do it slower again, not advice obviously 18:05
after a gap of more than about three weeks i restart one rung lower. thats my own rule, not advice
holding is not failing. most people here who lasted two years held at least one dose for months
New independent result logged — WXT, lot B-0114, purity 98.6% (PeptideMeter).
do you escalate on the calendar or on how you feel
medutest-report-d-0718.pdf
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unrelated but is there a point where going up stops buying you anything
the people who do best here are almost always the ones going slowest
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if you are asking whether to go up, the fact you are asking usually means not yet
plateau versus set point is not answerable in under six months of data, anyway
whats the longest anyone has stayed on one dose
is there any actual reason to escalate every 4 weeks other than the trial did it
if it "stopped working after four days" that is almost never pharmacokinetics
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half life is a week
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Reminder for ferrous_ash: dose day is today. Set 3 days ago.
i would hold
[edited][redacted at member request] · archive policy
how do you decide between holding and stepping when both feel wrong
Testing queue: 6 submissions open, 88 awaiting dispatch.
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has anyone gone up and then straight back down and been glad they tried
right so what does the room think about jumping a rung to catch up
site-rotation-map.png
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is week 32 too early to be thinking about the next step
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how much does the last dose still matter 8 days later
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i drifted from sunday to wednesday over a year and only noticed when i checked the log, thats just me
the argument for splitting is a flatter curve. the argument against is you have doubled your injections for a guess
update from 20 months ago: held at the same dose the whole time and still losing slowly
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nobody here can tell you what dose to be on and the ones who try get corrected
my rule: if a side effect is still there at day five, i hold. if it clears by day three, i step
i went from 1.7 to 10 and honestly could not tell the difference in appetite
if i hold at 12 indefinitely am i losing anything
no trial for that
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stepping back down on purpose is a completely reasonable move and this channel should say so more often, someone check my working
coming down from 10 to 7.5, how bad is the appetite rebound
dose day drift is mostly harmless with a weekly compound, but pick a day and defend it
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quick one a missed week does not reset you, but going straight back to the top dose after a gap is how people get floored
my titration ladder took 8 months to climb and i would do it slower again, not advice obviously
wk 1-4 0.25mg
wk 5-10 0.50mg (held 2 extra weeks)
wk 11-14 1.00mg
wk 15-26 1.70mg (held, long)
wk 27+ 2.40mgis there a trial anywhere that studied twice weekly, or is it all anecdote
the ladder in the trials is a starting point, not a schedule you owe anyone