#dosing-titration 2024-12-01

ok so the honest answer is that most of us are running protocols nobody has ever studied

whats a sensible maintenance dose after a year at treatment dose

if i hold at 10 indefinitely am i losing anything

the ladder in the trials is a starting point, not a schedule you owe anyone

pick a day and stick to it

thats normal

dose day drift is mostly harmless with a weekly compound, but pick a day and defend it

Purity check: no report on file for lot C-4402. Nothing logged either way.

i would hold

i drifted from sunday to wednesday over a year and only noticed when i checked the log

i went to the top of the ladder, felt no better than two rungs down, and came back. that is data for me and nobody else

half life is a week

how much does the last dose still matter 8 days later
plateau versus set point is not answerable in under six months of data

do you escalate on the calendar or on how you feel

came down, no regrets

thats anecdote

follow up whats the longest anyone has stayed on one dose

if i took it 9 days late do i shift the schedule or go back to the old day

thats noise

not advice

the people who do best here are almost always the ones going slowest

has anyone gone up and then straight back down and been glad they tried

is there a trial anywhere that studied twice weekly, or is it all anecdote

my rule: if a side effect is still there at day five, i hold. if it clears by day three, i step

came down from a treatment dose to maintenance over about three months and it was uneventful

i jumped a rung once to catch up after a supply gap and it was a bad week. would not repeat

slightly off topic but a missed week does not reset you, but going straight back to the top dose after a gap is how people get floored

coming back to this i have been at 0.5 for 3 months and honestly i have stopped wanting to move