the fasting window is the difference between a dose and a very expensive tablet
the non peptide orals are the interesting part of this channel now, not oral semaglutide
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#oral-glp1 2026-01-16
Friday31 messages8 participantstimes are UTC
Highlights from this day
- bp_down_bex — the fasting window is the difference between a dose and a very expensive tablet the non peptide orals are the interesting part of this channel now, not oral semaglutide 17:42
- lean_mass_lex — ok so my weekly log on oral is noisier than my injectable log ever was, same scales same mornings 17:54
- lean_mass_lex — i was wrong about the water amount, i was using a sip and it needs a lot more than that changed my mind on the plain water rule after reading how SNAC works, its not… 17:56
- vik_verifies — took mine with breakfast once by accident and that week was a write off 18:56
ok so my weekly log on oral is noisier than my injectable log ever was, same scales same mornings
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thirty minutes, no cheating
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i was wrong about the water amount, i was using a sip and it needs a lot more than that
changed my mind on the plain water rule after reading how SNAC works, its not a formality
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fasted every morning
i take mine at 6am, is 30 minutes really enough
does SNAC do anything other than get it through the stomach
went back to injecting because the morning routine was too fragile around shift work, thats one data point
right so the inconsistency is mostly technique and admitting that took me about a year
went back to injecting
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PIONEER not OASIS
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took mine with breakfast once by accident and that week was a write off
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big mg small dose
coffee is not plain water. i tried it for a month and my results got worse
not a peptide
follow up orforglipron is a small molecule rather than a peptide, which is why the fasting conditions differ
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OASIS ran under the same sort of fasting conditions, thats not the variable between the two
*Medutest not the other one
took 2 weeks before i saw anything on oral, roughly twice what the injection took me
quick one SNAC raises the local pH and protects it long enough to cross, thats its whole job
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PIONEER was the original oral semaglutide programme and OASIS looked at the higher oral doses
SNAC does the work
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changed my mind on the plain water rule after reading how SNAC works, its not a formality
nobody should copy my morning routine, but the timer is the bit i would keep, not advice obviously
ruined my breakfast
i use it because needles are a genuine problem for me, not because i think its better
is the non peptide thing why orforglipron doesnt need the fasting rules
the non peptide orals are the interesting part of this channel now, not oral semaglutide, thats just me
did anyone go back to injecting after trying oral
mine was patchy too
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oral was easier on my gut than injecting at what felt like a similar effect, which surprised me