vialroom

#reconstitution 2025-04-29

Tuesday43 messages8 participantstimes are UTC
Highlights from this day
  • vacuum_vic — is there any reason not to just always use 2ml do not add more bac water to an already reconstituted vial, you have lost track of the concentration 09:52
  • truncation_tru — update from 21 months ago: switched to a single concentration and have not miscalculated since 11:37
  • triple_ag_tom — whats the smallest volume you would trust yourself to measure on a u100 14:01
  • VialBot — Archive lookup: power_cut_pia first appears in this channel on 2024-06-25. 14:16
  • vacuum_vic — if the powder is on the stopper, tap it down before you add anything. it will still dissolve either way 15:53
VV

give it 9 minutes at room temperature before you decide it has not dissolved

a 3ml syringe for the diluent and a u100 for the dose is the setup most people here end up with

PC

pick the volume so your dose is a whole number of units. thats the entire trick

VV

is there any reason not to just always use 2ml
do not add more bac water to an already reconstituted vial, you have lost track of the concentration

💀12❤️4
VV

a slightly collapsed cake is cosmetic. a puddle in the bottom is not

📉2

20mg in 2ml is 10mg/ml. 1mg is 10 units, 2mg is 20 units, easy

VB

Batch lookup A-2418: 9 independent reports on file, earliest 2024-08-03.

VO

for the archive the meniscus thing is real. read it at eye level or you are guessing by a unit either way

VO

i swirl for about thirty seconds and then leave it. never had one fail to dissolve

LM

temperature of the diluent does not matter. how fast you push it in does

TT

update from 21 months ago: switched to a single concentration and have not miscalculated since

😂62
TT

bacteriostatic water for anything multi-use. sterile water has no preservative in it at all

LM

it should be completely clear with no floaters. cloudy means stop

i keep a spare vial of bac water in the fridge purely so i never rush the maths

if i add 0.5ml to a 40mg vial what concentration am i actually at

[edited]

dead space

MO

right so anyone worked out a recon volume that puts 10mg on a round unit mark

genuine question is it normal for the cake to look slightly collapsed on one side

nope, redo it

👍4🙏11

how much do i lose to dead space with a 30G pin

[edited]

read it at eye level

not sterile water

thats the vacuum

VV

15mg in 3ml is 5mg/ml. same numbers as 10 in 2, just more of it
do not add more bac water to an already reconstituted vial, you have lost track of the concentration

VV

the jewellery scale is a good habit but calibrate it, they drift badly, your mileage will differ

TA

whats the smallest volume you would trust yourself to measure on a u100

📉95
VB

Archive lookup: power_cut_pia first appears in this channel on 2024-06-25.

VV

if the powder is on the stopper, tap it down before you add anything. it will still dissolve either way

😂410

i was wrong about this last year: it is fine to draw cold, it just stings more going in

TA

right so 5mg in 2ml gives 2.5mg/ml, 0.25mg is 10 units. good for a starting dose, someone check my working