vialroom

#reconstitution 2025-05-01

Thursday30 messages7 participantstimes are UTC
Highlights from this day
  • batch_bandit — whats the smallest volume you would trust yourself to measure on a u100 16:50
  • VialBot — Assay note: JEEP lot H-2814 reported at 96.8% of label content. 18:13
  • VialBot — Reminder set. I will post here in 8 days. 18:48
MC

is it normal for the cake to look slightly collapsed on one side

BB

15mg in 3ml is 5mg/ml. same numbers as 10 in 2, just more of it, your mileage will differ

what do you do with the last 50 units when you cant draw them cleanly

whats the smallest volume you would trust yourself to measure on a u100

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TT

bac water or sterile water for something im going into weekly for 4 weeks

TT

if the powder is on the stopper, tap it down before you add anything. it will still dissolve either way
10mg in 1ml is 10mg/ml, so 2.5mg is 25 units. thats the one i use

VB

Archive lookup: meniscus_mel first appears in this channel on 2024-10-04.

MM

gross powder mass is not net peptide. water and counterion are in that number
benzyl alcohol is what makes it bacteriostatic. it is about 0.9% typically

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MM

lyophilised powder is far more robust than people think. it is the solution that is fragile

is it worth buying a 3ml syringe for the diluent or is the insulin one fine

is there any reason not to just always use 2ml

30mg in 3ml is 10mg/ml, so 5mg is 50 units. half the barrel, feels like a lot but its right

weighing the vial before you reconstitute is the only way to catch an underfill

i use bac water even for a single-use vial because it stings less, which is not the reason it exists

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U1

swirl it. do not shake it. the foam is denatured protein and you are not getting it back

follow up how much do i lose to dead space with a 31G pin

VB

Assay note: JEEP lot H-2814 reported at 96.8% of label content.

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MC

i keep a spare vial of bac water in the fridge purely so i never rush the maths

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genuine question 10mg in 1ml is 10mg/ml, so 2.5mg is 25 units. thats the one i use
weighing the vial before you reconstitute is the only way to catch an underfill

VB

Reminder set. I will post here in 8 days.

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MC

anyone got a photo of what a properly dissolved vial looks like

BB

benzyl alcohol is what makes it bacteriostatic. it is about 0.9% typically

slightly off topic but if the maths gives you 13.7 units, change the volume. do not try to hit 13.7

MC

i have never once regretted using a rounder number and a slightly bigger volume

do you draw up with the same pin you inject with