lost 33kg over 10 months at doses well under what the trials used
#retatrutide 2026-04-13
Monday45 messages11 participantstimes are UTC
Highlights from this day
- non_scale_win — triple agonist meaning GLP-1, GIP and glucagon, have i got that right 17:06
- mira_pins — is the glucagon arm what people mean by the energy expenditure thing 19:02
- quill_questions — reconstituted the 20 vial to 5mg/ml specifically so i could take 10 without measuring crumbs appetite suppression at 7.5 was stronger than my tirzepatide experience… 19:45
my resting rate went up 8 bpm in the first month and came back most of the way by month 6
the glucagon arm is the mechanistic story for extra energy expenditure and its still a story to me
16:21quiet.hours pinned a message to this channel
slightly off topic but whats the half life like, is it weekly the same way
no long term data
TRIUMPH is phase 3
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ok so my resting heart rate is up about 5 bpm, did that settle for anyone
held at 2.5 for 3 months and it never plateaued for me, which i cant explain
fridge-temps.csv
577 rows · not retained in the public archive
low and slow
stepping in 2.4 increments instead of doubling is the only thing i would change if i started again
does the glucagon arm explain the heart rate or is that unrelated
triple agonist meaning GLP-1, GIP and glucagon, have i got that right
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sat at 5 for 2 months rather than climbing and it kept working, so i never went up, happy to be corrected
whats a sensible starting point, im seeing everything from 0.5 to 2
is TRIUMPH the phase 3 programme
Purity check: no report on file for lot SG-1177. Nothing logged either way.
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nobody should read my log as a plan, im recording what i did and thats all it is
did the phase 2 result actually come in higher than the tirzepatide numbers
cant feel it honestly
energy expenditure isnt something i could feel, though my sleep tracker disagreed with me
anyone tracking blood pressure alongside the heart rate
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*PeptideMeter not the other one
how do people square the research use only framing with logging their own use
i log resting heart rate every morning because of this and its the one number i actually watch
Inter-lab diff for lot B-0329: 97.4% vs 96.8%. Within expected range.
buying this is a completely different risk conversation from the licensed compounds and that gets said too rarely, your mileage will differ
[edited]the honest position is this has less human evidence behind it than anything else discussed here
phase 2 doses are published and theyre not far off what people here run, coincidence rather than plan
came off at 17 weeks because my resting rate stayed elevated and i didnt like it
how slow is low and slow here, four weeks a step or longer
is the glucagon arm what people mean by the energy expenditure thing
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update on the earlier thing appetite suppression at 2 was stronger than my tirzepatide experience at a comparable point
i was wrong to call the heart rate a non issue last year, enough people logged it that i changed my mind
did the phase 2 plateau or was it still moving at the end
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the half life supports weekly dosing and thats what ive done from the start
settled by month three
reconstituted the 20 vial to 5mg/ml specifically so i could take 10 without measuring crumbs
appetite suppression at 7.5 was stronger than my tirzepatide experience at a comparable point
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anyone compared their VendorInvestigate purity across two different ERP lots
mine went up too
triple agonist, GLP-1 and GIP and glucagon. the glucagon arm is the part with no long history
the phase 2 weight result was larger than what the earlier agonists reported, in a smaller shorter trial
back after 3 months, has anything actually been published since
blood pressure stayed flat for me while heart rate moved, which i didnt expect, anyway
smaller steps here