cant feel it honestly
#retatrutide 2026-04-27
Monday35 messages9 participantstimes are UTC
Highlights from this day
- two_three_lifts — came off at 10 weeks because my resting rate stayed elevated and i didnt like it 15:14
- bea_reconstitutes — does the glucagon arm explain the heart rate or is that unrelated 15:18
- travel_cooler — anyone compared their VendorInvestigate purity across two different Homopeptide lots 15:35
update on the earlier thing my resting heart rate is up about 7 bpm, did that settle for anyone
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unrelated but anyone gone above 2.5 and what changed
back after 25 months, has anything actually been published since
glucagon is the new bit
*Medutest not the other one
did the phase 2 plateau or was it still moving at the end
low and slow
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came off at 10 weeks because my resting rate stayed elevated and i didnt like it
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is TRIUMPH the phase 3 programme
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watching my heart rate
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does the glucagon arm explain the heart rate or is that unrelated
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phase 2 was still trending at the end which is why the phase 3 readout matters more than usual
no idea whether the heart rate settles for everyone, mine did and one log isnt data
anyone compared their VendorInvestigate purity across two different Homopeptide lots
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there is no long term safety data, phase 2 and an ongoing phase 3 programme is what exists
i was wrong to call the heart rate a non issue last year, enough people logged it that i changed my mind
triple agonist, GLP-1 and GIP and glucagon. the glucagon arm is the part with no long history
the half life supports weekly dosing and thats what ive done from the start
smaller steps here
mine went up too
the phase 2 weight result was larger than what the earlier agonists reported, in a smaller shorter trial
research use only is on every vial and i treat it as exactly that, nobody here is prescribing
settled by month three
no idea whether the heart rate settles for everyone, mine did and one log isnt data
low and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom
18:03quiet.hours pinned a message to this channel
why does everyone insist on smaller steps here than on the other two
logging rhr daily
phase 2 doses are published and theyre not far off what people here run, coincidence rather than plan
*VendorInvestigate not the other one
the glucagon arm is the mechanistic story for extra energy expenditure and its still a story to me
my resting rate went up 7 bpm in the first month and came back most of the way by month 10
no long term data
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research use only
did the phase 2 result actually come in higher than the tirzepatide numbers