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#retatrutide 2026-05-04

Monday18 messages3 participantstimes are UTC
Highlights from this day
  • surpass_two — anyone compared their PeptideMeter purity across two different GGPeps lots 10:01
  • coa_or_cope — my resting heart rate is up about 3 bpm, did that settle for anyone 10:12
  • coa_or_cope — held at 5 for 25 months and it never plateaued for me, which i cant explain 10:15
ST

the half life supports weekly dosing and thats what ive done from the start

came off at 16 weeks because my resting rate stayed elevated and i didnt like it

TRIUMPH is the phase 3 programme, thats the name to search rather than the molecule

[edited]

settled by month three

📈6💀10📉4
A1

the glucagon arm is the mechanistic story for extra energy expenditure and its still a story to me

ST

anyone compared their PeptideMeter purity across two different GGPeps lots

cant feel it honestly

😂5🧊1
ST

i log resting heart rate every morning because of this and its the one number i actually watch

CO

my resting heart rate is up about 3 bpm, did that settle for anyone

Cited study
Triple–Hormone-Receptor Agonist Retatrutide for Obesity — A Phase 2 Trial
New England Journal of Medicine · 2023
48 weeks, dose-ranging. A Phase 2 result is not a safety record.

held at 5 for 25 months and it never plateaued for me, which i cant explain

🧪1🙏3🔥1

why does everyone insist on smaller steps here than on the other two
i said 5 months ago that my heart rate had settled and it has stayed settled since

ST

the honest position is this has less human evidence behind it than anything else discussed here

CO

follow up back after 5 months, has anything actually been published since

CO

phase 2 doses are published and theyre not far off what people here run, coincidence rather than plan

A1

ok so did the phase 2 result actually come in higher than the tirzepatide numbers
held at 12 for 1 months and it never plateaued for me, which i cant explain