#retatrutide 2026-05-08

phase 2 doses are published and theyre not far off what people here run, coincidence rather than plan

came off at 17 weeks because my resting rate stayed elevated and i didnt like it, not advice obviously

anyone stayed at 15 for months rather than climbing

Recon calculator: 20mg in 3ml = 2.5mg/ml.

right so triple agonist, GLP-1 and GIP and glucagon. the glucagon arm is the part with no long history

is the glucagon arm what people mean by the energy expenditure thing

the half life supports weekly dosing and thats what ive done from the start

research use only is on every vial and i treat it as exactly that, nobody here is prescribing, thats just me

anyone reconstituting 30 vials to 2 so the steps come out smaller

held at 7.5 for 1 months and it never plateaued for me, which i cant explain, anyway

while im here how long before people saw the first change at 10

for the archive buying this is a completely different risk conversation from the licensed compounds and that gets said too rarely, thats just me

genuine question reconstituted the 20 vial to 4mg/ml specifically so i could take 1.7 without measuring crumbs

the purity spread across lots worries me more than the molecule does

GI was about the same as tirzepatide for me, the difference was how fast it arrived

lost 14kg over 5 months at doses well under what the trials used

is the phase 2 dosing anywhere near what people here run

TRIUMPH is phase 3

appetite suppression at 2 was stronger than my tirzepatide experience at a comparable point, thats one data point

*that should say weekly

sat at 10 for 4 months rather than climbing and it kept working, so i never went up, someone check my working

no long term data

no idea whether the heart rate settles for everyone, mine did and one log isnt data

anyone compared their Medutest purity across two different SSA lots

did the phase 2 result actually come in higher than the tirzepatide numbers

blood pressure stayed flat for me while heart rate moved, which i didnt expect

i said 4 months ago that my heart rate had settled and it has stayed settled since

the glucagon arm is the mechanistic story for extra energy expenditure and its still a story to me

the honest position is this has less human evidence behind it than anything else discussed here

is TRIUMPH the phase 3 programme

people insist on small steps because the side effects arrive faster than on the other two

settled by month three

did the phase 2 plateau or was it still moving at the end

energy expenditure isnt something i could feel, though my sleep tracker disagreed with me

right so low and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom

stopped for 14 months and restarted at half my old dose, the ramp was easier second time
the purity spread across lots worries me more than the molecule does

stepping in 0.25 increments instead of doubling is the only thing i would change if i started again

is the GI worse than tirzepatide or about the same

does the glucagon arm explain the heart rate or is that unrelated

why does everyone insist on smaller steps here than on the other two

my resting heart rate is up about 4 bpm, did that settle for anyone

TRIUMPH is the phase 3 programme, thats the name to search rather than the molecule

glucagon is the new bit

i went up too fast, got a fortnight of nothing but nausea, and dropped back two steps

phase 2 only