held mine ages
#retatrutide 2026-06-16
Tuesday35 messages7 participantstimes are UTC
Highlights from this day
- manila_meniscus — triple agonist, GLP-1 and GIP and glucagon. the glucagon arm is the part with no long history, i have it written down somewhere 15:35
- manila_meniscus — genuine question nobody should read my log as a plan, im recording what i did and thats all it is, happy to be corrected 15:54
- typosquat_tay — for the archive is TRIUMPH the phase 3 programme 16:04
- typosquat_tay — lost 42kg over 13 months at doses well under what the trials used 16:13
- VialBot — Recon calculator: 2mg in 1.5ml = 8mg/ml. 16:32
TRIUMPH is phase 3
triple agonist, GLP-1 and GIP and glucagon. the glucagon arm is the part with no long history, i have it written down somewhere
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*VendorInvestigate not the other one
sorry to jump in i said 8 months ago that my heart rate had settled and it has stayed settled since
genuine question nobody should read my log as a plan, im recording what i did and thats all it is, happy to be corrected
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sat at 1 for 2 months rather than climbing and it kept working, so i never went up
the heart rate thing is real enough that i mention it whenever someone asks about starting
*Janoshik not the other one
for the archive is TRIUMPH the phase 3 programme
baseline 58
wk 2 61
wk 4 64
wk 6 67
wk 8 66
wk 10 65 (held dose from wk 7)did the phase 2 plateau or was it still moving at the end
the phase 2 weight result was larger than what the earlier agonists reported, in a smaller shorter trial
lost 42kg over 13 months at doses well under what the trials used
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i log resting heart rate every morning because of this and its the one number i actually watch
low and slow
the glucagon arm is the mechanistic story for extra energy expenditure and its still a story to me
smaller steps here
settled by month three
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phase 2 only
Recon calculator: 2mg in 1.5ml = 8mg/ml.
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triple agonist yeah
right so no idea whether the heart rate settles for everyone, mine did and one log isnt data, thats just me
low and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom
blood pressure stayed flat for me while heart rate moved, which i didnt expect
people insist on small steps because the side effects arrive faster than on the other two
anyone gone above 5 and what changed
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my resting rate went up 6 bpm in the first month and came back most of the way by month 21
is the GI worse than tirzepatide or about the same
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TRIUMPH is the phase 3 programme, thats the name to search rather than the molecule
appetite suppression at 2.4 was stronger than my tirzepatide experience at a comparable point, someone check my working
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how long before people saw the first change at 0.5
research use only
held at 15 for 22 months and it never plateaued for me, which i cant explain
the honest position is this has less human evidence behind it than anything else discussed here
did anyone come off because of the heart rate