vialroom

#semaglutide 2025-07-16

Wednesday23 messages6 participantstimes are UTC
Highlights from this day
  • warsaw_vial — for the archive anyone gone from 1.7 straight to 0.5 or is that too big a jump 10:37
  • warsaw_vial — SELECT was cardiovascular outcomes in people with overweight and existing disease, not a weight trial, ymmv 12:19
  • warsaw_vial — quick one is the plateau at 18 weeks normal or am i doing something wrong i dont think the plateau is a dose problem most of the time, but i cant prove that 12:21
  • VialBot — Channel stats, last 30 days: 26 messages from 12 members. 12:36
  • half_life_hal — my Janoshik report on the TFC vial came back 99.2 against a certificate saying 97.4 12:38

steady state takes weeks

for the archive anyone gone from 1.7 straight to 0.5 or is that too big a jump

🧪3🔥5
HL

restarted after 13 months off at a low dose and the nausea arrived exactly like the first time

DD

unrelated but the trials titrated on a fixed schedule, most people here dont, worth remembering when comparing

⚠️1

2.4 is the ceiling

WV

what did SELECT actually measure, i see it quoted for everything

LT

went 1 to 1.7 too fast and spent two weeks regretting it, dropped back and repeated the step

not the same trial

😂17❤️5
MC

ok so does moving my dose day by two days matter with a seven day half life

WV

vials not pens here

Trial scheduleWhat most people here do
Step interval4 weeks, fixed4-12 weeks, on symptoms
Holdingprotocol deviationnormal and expected
Top dosereached by designoften never reached
Coming downnot studiedcommon at maintenance
WV

SELECT was cardiovascular outcomes in people with overweight and existing disease, not a weight trial, ymmv

Trial scheduleWhat most people here do
Step interval4 weeks, fixed4-12 weeks, on symptoms
Holdingprotocol deviationnormal and expected
Top dosereached by designoften never reached
Coming downnot studiedcommon at maintenance

quick one is the plateau at 18 weeks normal or am i doing something wrong
i dont think the plateau is a dose problem most of the time, but i cant prove that

DD

compounded and brand felt the same to me at 2.4, which is one person and nothing more, we shall see

[edited]

slower worked better

fridge-thermometer.png
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📈7
VB

Channel stats, last 30 days: 26 messages from 12 members.

⚠️18
HL

my Janoshik report on the TFC vial came back 99.2 against a certificate saying 97.4

🤝17👀2

held there too