SELECT wasnt weight
#semaglutide 2025-12-10
Wednesday31 messages5 participantstimes are UTC
Highlights from this day
- pioneer_pia — my dose day drifted from friday to sunday, does that reset anything 17:44
- pioneer_pia — did anybody find a difference between ERP and pharmacy at the same 0.25 17:47
- apnoea_down_two — i was wrong about the ceiling for a year, i thought 3 existed. it doesnt for the weight indication 18:20
does the licensed ceiling for weight differ from the diabetes one
licensed ceiling for weight is 2.4 weekly, anything above that is not a licensed dose
vials not pens here
not the same trial
same dose day
half life is about a week so youre roughly four to five weeks to steady state on any new dose
sorry to jump in compounded and brand felt the same to me at 1.7, which is one person and nothing more
STEP 1 ran to 68 weeks. thats the one everyone half remembers
vial units and pen clicks are different systems, mixing the two is how people end up wrong
seven days ish
went to 2.4 and the extra suppression wasnt worth the GI for me, so i came back down
12 months at 2.4 and the honest summary is diminishing returns after the first half, your mileage will differ
*Janoshik not the other one
im 20 months in at 10 and the appetite effect faded, is that a thing
does the seven day half life mean the last two days are weaker
steady state is the bit people skip, judging a new dose after eight days tells you almost nothing, ill dig out the number
give it four weeks
slower worked better
| Trial schedule | What most people here do | |
|---|---|---|
| Step interval | 4 weeks, fixed | 4-12 weeks, on symptoms |
| Holding | protocol deviation | normal and expected |
| Top dose | reached by design | often never reached |
| Coming down | not studied | common at maintenance |
my dose day drifted from friday to sunday, does that reset anything
🔥6
did anyone titrate slower than four weeks a step and how did that go
did anybody find a difference between ERP and pharmacy at the same 0.25
thats STEP 1
moving my dose day by a day or two never did anything noticeable for me
i was wrong about the ceiling for a year, i thought 3 existed. it doesnt for the weight indication
📈1👍3
went too fast once
unrelated but is the plateau at 22 weeks normal or am i doing something wrong
2.4 is the ceiling
🧊6
mine faded too
🧊12
held there too
🧊10
STEP is several trials, so saying STEP said x is usually wrong without a number after it
the plateau hit me at 7 weeks and moved again about a month later without a dose change