my 2 vial in 2ml gives 4mg/ml so 10 lands on 12 units, thats why i picked that volume
#semaglutide 2025-12-16
Tuesday35 messages9 participantstimes are UTC
Highlights from this day
- VialBot — Assay note: SSA lot A-2418 reported at 99.2% of label content. 18:06
- night_pin — the long half life flattens the trough more than people expect, i never felt a day seven dip 18:52
- reed_reta — £240 a month for compounded against what brand costs locally is why most people here use vials 20:10
- egfr_ed — i held at 12 for 5 months and it was the best decision i made 20:46
Assay note: SSA lot A-2418 reported at 99.2% of label content.
sorry to jump in restarted after 24 months off at a low dose and the nausea arrived exactly like the first time
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how did people handle the jump from 1 to 1.7
Batch lookup SG-1177: 5 independent reports on file, earliest 2025-05-15.
update on the earlier thing i was wrong about the ceiling for a year, i thought 3 existed. it doesnt for the weight indication
how long till steady state, ive read the half life is about a week
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changed my mind on the four week rule, i think it depends entirely on how the current dose feels
right so did anyone titrate slower than four weeks a step and how did that go
my plateau was the scale stopping while appetite stayed suppressed, which is a different problem
the long half life flattens the trough more than people expect, i never felt a day seven dip
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2.4 is the ceiling
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is the plateau usually appetite coming back or just the scale stopping
the plateau hit me at 27 weeks and moved again about a month later without a dose change
i stayed on 1.7 for 6 months and never went to 2.4, appetite was already where i needed it
[edited]while im here if youre comparing brand to compounded, dose accuracy in the vial is the variable, not the molecule
the appetite effect faded for me around 2 months and going up fixed it for a while
does the seven day half life mean the last two days are weaker
licensed ceiling for weight is 2.4 weekly, anything above that is not a licensed dose
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£240 a month for compounded against what brand costs locally is why most people here use vials
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did the STEP 4 withdrawal arm show what i think it showed
going slow cost me nothing except time and saved me two bad weeks, thats my whole contribution
while im here im at 5 and stuck, did anyone break a plateau without going up
give it four weeks
compounded and brand felt the same to me at 10, which is one person and nothing more
how many weeks before you noticed anything at 1.7
i held at 12 for 5 months and it was the best decision i made
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held there too
seven days ish
is there a reason to hold at 1.7 rather than going to 2.4
same dose day
| Trial schedule | What most people here do | |
|---|---|---|
| Step interval | 4 weeks, fixed | 4-12 weeks, on symptoms |
| Holding | protocol deviation | normal and expected |
| Top dose | reached by design | often never reached |
| Coming down | not studied | common at maintenance |
does anyone actually run a five week step instead of four
back after 10 months off, do i restart at 0.25 or somewhere higher
slower worked better