vialroom

#storage-coldchain 2026-06-03

Wednesday21 messages6 participantstimes are UTC
Highlights from this day
  • taper_or_not — genuine question does anyone freeze reconstituted vials or is that madness 14:42
  • taper_or_not — i have never had a lyophilised vial fail after a warm transit and i have had some bad ones 14:57
  • noct.titrate — update on the earlier thing lyophilised powder is genuinely robust. a warm transit is far less likely to matter than people fear 15:01
  • pbs_pip — genuine question update from 9 months ago: replaced the fridge, temperature is stable, no more anxiety 17:42
  • vale_vials — a liquid cold pack tells you it was above freezing, not that your vial cooked 17:55
PP

the practical risk in winter shipping is freezing, and in summer it is heat. plan for the season you are in

AA

unopened and in-use in the same place is fine. just keep the in-use one where you can reach it

TO

genuine question does anyone freeze reconstituted vials or is that madness

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TO

buy a thermometer. mine reads 3.1 on the door and two degrees lower at the back, anyway

i have never had a lyophilised vial fail after a warm transit and i have had some bad ones

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NT

update on the earlier thing lyophilised powder is genuinely robust. a warm transit is far less likely to matter than people fear

mon  4.1 / door 7.2
tue  4.0 / door 7.8
wed  4.2 / door 6.9
thu  3.9 / door 7.4
fri  4.1 / door 8.1   <- shopping day
sat  4.3 / door 7.0
sun  4.0 / door 6.8
FF

light exposure matters much less than temperature for these. i still keep them in the carton

two to eight degrees. most domestic fridge doors are not in that range and people do not check

TO

if you are worried after a bad transit, test it. that is what the testing channels are for

NT

a cooler with two gel packs held under eight degrees for eleven hours on a drive

PP

genuine question update from 9 months ago: replaced the fridge, temperature is stable, no more anxiety

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a few hours at room temperature is almost certainly nothing. a week is a different conversation

*week 19 not week 4

a liquid cold pack tells you it was above freezing, not that your vial cooked

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