#tirzepatide 2025-01-05

for the archive 12 did nothing extra over 10 for me and that still holds a year later, happy to be corrected

unrelated but i went to 15 and came back to 10, more suppression wasnt more useful for me, n of 1 obviously
i log everything and my appetite curve looks flatter across the week than my semaglutide log did

the trials titrated every four weeks to a target, most people here stop at whatever works

anyone got a 10 recon they like for the 20 vials

held 10 for 25 months and lost 40kg over that stretch, slow and boring and fine

coming off semaglutide, is there a conversion or do i restart at 2.5

how long before the dual thing was noticeable to you

im on sema 1.7. if i switch to tirz what dose is equivalent

there isnt one

there must be some conversion

there genuinely is not. different receptor targets, different half-lives, different dose response shapes

people post them constantly and they never cite anything, because there is nothing to cite

i have seen 2.4 sema mapped to 10 tirz and also to 5 tirz, in the same week, by people equally confident

so what do people actually do

most of us restart the ladder. 2.5 tirz for four weeks even coming off a high sema dose

which feels like going backwards and it mostly isnt, because sema is still clearing for a month

thats the key bit. week one on tirz you are on tirz plus most of your last sema dose

oh. so the overlap does the work

yes, and people who jump straight in at 7.5 discover this the hard way in week two

i did jump straight in at 7.5. i do not recommend the week i had

not dangerous, just genuinely miserable. four days of not wanting water

and if you cant keep water down that stops being a chat question and starts being a doctor question

agreed, and i should have said that myself

did switching actually help you

for me yes. sema had stalled for four months and tirz moved me again

for me no. i switched, lost nothing extra, and had worse constipation. switched back after five weeks

which is why nobody in here will tell you it works. it works for some people

how do you know if youre one of them

you try it for long enough to know and you keep a log so you can tell the difference between a stall and a slow month

*five months not five weeks, sorry. it was long enough to be a fair try

on supply, the TFC material i moved to was fine, and going back to a pen later was uneventful

worth stating plainly: research material is not approved for human use. everyone here knows that and it stays true no matter how good a COA looks

yep

you were right that there was no conversion and i went and looked. every table i found traced back to a single unsourced graphic

welcome to most of the internet on this subject

good digging though. thats the standard in here