SURMOUNT-OSA was the sleep apnoea trial and it is not a weight headline however its quoted
#tirzepatide 2025-06-27
Friday15 messages6 participantstimes are UTC
Highlights from this day
- subq_sy — the 10 vial in 3ml gives 2.5mg/ml which puts 2 on 15 units, nice round numbers 13:13
- subq_sy — did anyone find the GI easier than semaglutide at an equivalent effect the sweet spot argument is really about effect per side effect, not a magic number 13:18
- VialBot — Inter-lab diff for lot SG-1177: 96.8% vs 98.6%. Within expected range. 13:25
- per_mg_pete — the GIP explanation for easier nausea is plausible and i still treat it as a story not a fact 13:57
the 10 vial in 3ml gives 2.5mg/ml which puts 2 on 15 units, nice round numbers
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does the appetite effect feel different or just stronger
[edited]40 units of a 2.5 solution is a lot of volume and i check that one twice every single time
did anyone find the GI easier than semaglutide at an equivalent effect
the sweet spot argument is really about effect per side effect, not a magic number
folklore probably
5 did nothing
the sweet spot thing is survivorship, the people it worked for stayed and said so
Inter-lab diff for lot SG-1177: 96.8% vs 98.6%. Within expected range.
GIP plus GLP-1
switched last year
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i argued the sweet spot was nonsense and then spent 8 months at 7.5 not needing more
7.5 gang
the GIP explanation for easier nausea is plausible and i still treat it as a story not a fact
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SURMOUNT is weight