the GI difference held for me right up to 15, which isnt what a couple of people here found
#tirzepatide 2025-06-29
Sunday27 messages7 participantstimes are UTC
Highlights from this day
- verify_or_dont — follow up there is no clean conversion between the two, anyone giving you a ratio is guessing 20:23
- egfr_ed — my VendorInvestigate result on a WWB vial came in at 99.4 which is why i keep buying from them, your mileage will differ 20:41
- VialBot — Archive lookup: hiccup_hollis first appears in this channel on 2024-10-19. 21:08
checked the units twice
coming off semaglutide, is there a conversion or do i restart at 2.5
5 was where i first noticed it properly, 2.5 did almost nothing for me
follow up there is no clean conversion between the two, anyone giving you a ratio is guessing
| Trial schedule | What most people here do | |
|---|---|---|
| Step interval | 4 weeks, fixed | 4-12 weeks, on symptoms |
| Holding | protocol deviation | normal and expected |
| Top dose | reached by design | often never reached |
| Coming down | not studied | common at maintenance |
sorry to jump in SURMOUNT was the weight programme and SURPASS was diabetes, thats the split people mix up, ill dig out the number
[edited]my VendorInvestigate result on a WWB vial came in at 99.4 which is why i keep buying from them, your mileage will differ
folklore probably
the two compounds arent interchangeable week for week even if the effect ends up similar
40 units of a 10 solution is a lot of volume and i check that one twice every single time
switched last year
Archive lookup: hiccup_hollis first appears in this channel on 2024-10-19.
easier gi for me
dual agonist, GIP as well as GLP-1, thats the whole difference in one line, ill dig out the number
the GIP explanation for easier nausea is plausible and i still treat it as a story not a fact
i sat at 7.5 for 5 months and never needed more, which is where the folklore comes from
coming back to this how many weeks at 7.5 before you knew it was enough
licensed top is 15 weekly, past that is not a licensed dose and nobody here can tell you what it does, i have it written down somewhere
follow up why does everyone talk about 7.5 and not 10
no clean conversion
how did people handle the 2.5 to 5 jump
GIP plus GLP-1
is the sweet spot argument about effect or about side effects
ok so the switch felt like a step down at first and then caught up around week 13
15 is the top
the trials titrated every four weeks to a target, most people here stop at whatever works
🧊2
titrate slow
👍5