SURMOUNT is weight
peptidemeter-summary-h-2814.pdf
2 pages · 660 KB · not retained in the public archive
#tirzepatide 2025-07-28
Monday14 messages4 participantstimes are UTC
Highlights from this day
- back_from_away — the trials titrated every four weeks to a target, most people here stop at whatever works held 10 for 22 months and lost 47kg over that stretch, slow and boring and… 12:47
- logrotate — restarted at 2.5 after 10 months off and the first two doses reminded me why titration exists, i think 14:10
- third_shift — whats the plateau pattern here, same as semaglutide or different 14:15
how did people handle the 2.5 to 5 jump
held 10 for 5 months and lost 6kg over that stretch, slow and boring and fine
15 is the top
the sweet spot thing is survivorship, the people it worked for stayed and said so
went back to semaglutide after 14 months because the cost difference mattered more than the GI
i sat at 7.5 for 13 months and never needed more, which is where the folklore comes from
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whats the top licensed dose, 15 or does it go higher
the trials titrated every four weeks to a target, most people here stop at whatever works
held 10 for 22 months and lost 47kg over that stretch, slow and boring and fine
restarted at 2.5 after 10 months off and the first two doses reminded me why titration exists, i think
peptidemeter-summary-d-0718.pdf
2 pages · 277 KB · not retained in the public archive
im at 12 and thinking about 7.5, did anyone gain anything from that step
whats the plateau pattern here, same as semaglutide or different
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titrate slow
| Trial schedule | What most people here do | |
|---|---|---|
| Step interval | 4 weeks, fixed | 4-12 weeks, on symptoms |
| Holding | protocol deviation | normal and expected |
| Top dose | reached by design | often never reached |
| Coming down | not studied | common at maintenance |
GIP plus GLP-1