the 15 vial in 3ml gives 2mg/ml which puts 7.5 on 50 units, nice round numbers
#tirzepatide 2025-09-18
Thursday31 messages9 participantstimes are UTC
Highlights from this day
- vialkeeper — follow up anyone tracked whether the GI difference held at the top doses 13:50
- karl_fischer — the two compounds arent interchangeable week for week even if the effect ends up similar 14:36
- drawup_dee — i went to 15 and came back to 10, more suppression wasnt more useful for me 16:41
- drawup_dee — plateaued at 13 weeks the same way i did on semaglutide, so i doubt its compound specific, from memory 16:43
*Medutest not the other one
7.5 gang
is 7.5 really the sweet spot or is that just channel folklore
10 was enough
no clean conversion
did anyone go past 15 and was there any point to it
unrelated but the GIP explanation for easier nausea is plausible and i still treat it as a story not a fact
[edited]*Janoshik not the other one
for the archive is the sweet spot argument about effect or about side effects
coming off semaglutide, is there a conversion or do i restart at 2.5
at 15 the GI came back for me, so my easier profile claim only applies below that
i log everything and my appetite curve looks flatter across the week than my semaglutide log did
start low anyway
SURMOUNT-OSA was the sleep apnoea trial and it is not a weight headline however its quoted
15 is the top
follow up anyone tracked whether the GI difference held at the top doses
🔥10🎉13📉1
dual agonist, GIP as well as GLP-1, thats the whole difference in one line
switched last year
the two compounds arent interchangeable week for week even if the effect ends up similar
how did people handle the 2.5 to 5 jump
SURMOUNT was the weight programme and SURPASS was diabetes, thats the split people mix up
the sweet spot argument is really about effect per side effect, not a magic number
restarted at 2.5 after 21 months off and the first two doses reminded me why titration exists
i went to 15 and came back to 10, more suppression wasnt more useful for me
wk 1-4 2.5mg
wk 5-8 5.0mg
wk 9-20 7.5mg <- stayed here
wk 21-24 10.0mg (no extra benefit for me)
wk 25+ 7.5mg (came back down)✅1
plateaued at 13 weeks the same way i did on semaglutide, so i doubt its compound specific, from memory
👍18
5 did nothing
the switch felt like a step down at first and then caught up around week 23
at 7.5 my appetite is gone entirely, did anyone go down rather than up
🧪1✅2
Reminder set. I will post here in 3 days.
12 did nothing extra over 10 for me and that still holds a year later
how long before the dual thing was noticeable to you