no gap when i switched, took the last semaglutide dose and started this a week later
#tirzepatide 2026-02-24
Tuesday20 messages5 participantstimes are UTC
Highlights from this day
- bench_notes — my Medutest result on a Homopeptide vial came in at 99.4 which is why i keep buying from them 20:13
- dexa_or_bia — restarted at 2.5 after 23 months off and the first two doses reminded me why titration exists 20:26
- fibre_first — GI was noticeably easier for me than semaglutide at what felt like the same appetite effect, i think 20:32
- impersonator_ip — is the sweet spot argument about effect or about side effects 22:33
i argued the sweet spot was nonsense and then spent 12 months at 7.5 not needing more
did going from 2.4 semaglutide to 5 of this feel like a step down for anyone
is SURMOUNT-OSA the sleep apnoea one
GIP plus GLP-1
my Medutest result on a Homopeptide vial came in at 99.4 which is why i keep buying from them
titrate slow
12 did nothing extra over 10 for me and that still holds a year later, thats one data point
is the 10 vial the common one or do people use 40
restarted at 2.5 after 23 months off and the first two doses reminded me why titration exists
GI was noticeably easier for me than semaglutide at what felt like the same appetite effect, i think
plateaued at 10 weeks the same way i did on semaglutide, so i doubt its compound specific
same plateau here
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how long before the dual thing was noticeable to you
did anybody switch back to semaglutide after trying this
no clean conversion
how did people handle the 2.5 to 5 jump
does the GIP arm actually explain the easier nausea or is that hand waving
is the sweet spot argument about effect or about side effects
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dual agonist, GIP as well as GLP-1, thats the whole difference in one line, i think