the two compounds arent interchangeable week for week even if the effect ends up similar
went back to semaglutide after 18 months because the cost difference mattered more than the GI
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#tirzepatide 2026-06-11
Thursday16 messages4 participantstimes are UTC
Highlights from this day
- plateau_pen — the two compounds arent interchangeable week for week even if the effect ends up similar went back to semaglutide after 18 months because the cost difference mattered… 18:06
- munich_mgml — no gap when i switched, took the last semaglutide dose and started this a week later, still working it out 18:31
- munich_mgml — coming back to this went back to semaglutide after 20 months because the cost difference mattered more than the GI 18:49
GI was noticeably easier for me than semaglutide at what felt like the same appetite effect
whats the plateau pattern here, same as semaglutide or different
no gap when i switched, took the last semaglutide dose and started this a week later, still working it out
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GIP plus GLP-1
no clean conversion
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the sweet spot argument is really about effect per side effect, not a magic number
is SURMOUNT-OSA the sleep apnoea one
switched last year
coming back to this went back to semaglutide after 20 months because the cost difference mattered more than the GI
how long before the dual thing was noticeable to you
whats the top licensed dose, 15 or does it go higher
unrelated but restarted at 2.5 after 15 months off and the first two doses reminded me why titration exists
the sweet spot thing is survivorship, the people it worked for stayed and said so, for what its worth
at 15 the GI came back for me, so my easier profile claim only applies below that
same plateau here